Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 2/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22248357 | 0.95 | ROCK2 (0.35) | ROCK2JAK2SYKNAMPTFAAH | |
| SCHEMBL22249152 | 0.91 | ROCK2 (0.38) | ROCK2KDM1AMAOBRCOR1JAK2 | |
| SCHEMBL22249141 | 0.91 | ROCK2 (0.38) | ROCK2KDM1AMAOBRCOR1JAK2 | |
| SCHEMBL22248333 | 0.90 | ROCK2 (0.36) | ROCK2JAK2SYKNAMPTFAAH | |
| SCHEMBL22248886 | 0.89 | NAMPT (0.34) | ROCK2POLBNAMPTFAAHDGAT1 | |
| SCHEMBL22248293 | 0.87 | ROCK2 (0.36) | ROCK2KDM1AMAOBRCOR1FAAH | |
| SCHEMBL22248752 | 0.87 | ROCK2 (0.34) | ROCK2NAMPTFAAHDGAT1 | |
| Hydrochloric Acid SCHEMBL30276601 | 0.86 | ROCK2 (0.34) | ROCK2NAMPTFAAHDGAT1 | |
| SCHEMBL22254186 | 0.86 | ROCK2 (0.35) | ROCK2KDM1AMAOBRCOR1POLB | |
| SCHEMBL22249119 | 0.86 | KDM1A (0.45) | KDM1AMAOBRCOR1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |