Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 10/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
| ▸ | PAICS | P22234 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22248357 | 0.93 | ROCK2 (0.35) | ROCK2JAK2SYKFAAHNAMPT | |
| SCHEMBL22249145 | 0.90 | ROCK2 (0.36) | ROCK2JAK2SYKFAAHNAMPT | |
| SCHEMBL22248413 | 0.88 | HPGD (0.36) | ROCK2FAAHIKBKETBK1 | |
| SCHEMBL22248295 | 0.88 | ROCK2 (0.38) | ROCK2FAAHF10 | |
| SCHEMBL22249152 | 0.87 | ROCK2 (0.38) | ROCK2JAK2SYKFAAHENPP2 | |
| SCHEMBL22249141 | 0.87 | ROCK2 (0.38) | ROCK2JAK2SYKFAAHENPP2 | |
| SCHEMBL22248293 | 0.87 | ROCK2 (0.36) | ROCK2FAAHIKBKETBK1 | |
| SCHEMBL22249044 | 0.87 | FAAH (0.35) | ROCK2FAAHNAMPTDGAT1 | |
| SCHEMBL22248665 | 0.87 | KDM1A (0.37) | FAAH | |
| SCHEMBL22248411 | 0.87 | CXCR4 (0.39) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |