SCHEMBL22249696

SCHEMBL22249696

CC1(C)OB(c2cnc3oc4cc5c6ccccc6c6ccccc6c5cc4c3c2)OC1(C)C

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LPL P06858 7/20 0.37
LIPG Q9Y5X9 7/20 0.37
PDGFRB P09619 2/20 0.36
KDR P35968 2/20 0.36
DGAT1 O75907 2/20 0.35
GSK3A P49840 1/20 0.35
GSK3B P49841 1/20 0.35
CSF1R P07333 1/20 0.34
ALPL P05186 1/20 0.34
EGFR P00533 1/20 0.33
PRMT5 O14744 1/20 0.32
WDR77 Q9BQA1 1/20 0.32
IRAK4 Q9NWZ3 1/20 0.31
AAK1 Q2M2I8 1/20 0.30
ALDH2 P05091 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17628524 0.88 LPL (0.40) LPLLIPGPDGFRBKDRDGAT1
SCHEMBL32671782 0.88 LPL (0.40) LPLLIPGPDGFRBKDRDGAT1
SCHEMBL20109580 0.80 LPL (0.45) LPLLIPGCSF1REGFRPRMT5
SCHEMBL22155557 0.77 LPL (0.43) LPLLIPGCSF1REGFRPRMT5
SCHEMBL21066305 0.77 LPL (0.45) LPLLIPGCSF1RPRMT5WDR77
SCHEMBL19794332 0.75 DGAT1 (0.48) LPLLIPGPDGFRBKDRDGAT1
SCHEMBL18015442 0.74 KDM4E (0.42) LPLLIPGCSF1REGFRPRMT5
SCHEMBL20321608 0.72 LPL (0.46) LPLLIPGCSF1REGFRPRMT5
SCHEMBL2015694 0.72 LPL (0.56) LPLLIPGCSF1REGFRPRMT5
SCHEMBL15456760 0.72 LPL (0.56) LPLLIPGCSF1REGFRPRMT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200235306-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2020-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200235306-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME OR10J3, PIEZO1, ODC1 LPL 2133/4885LIPG 2787/4885PDGFRB 4863/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.