SCHEMBL22250089

SCHEMBL22250089

CC(C)c1nc(-c2ccc(-c3ccc(-c4ccccc4)cc3)cc2)nc(-c2cccc(-c3ccccc3)c2)n1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.46
RXRA P19793 1/20 0.45
RXRB P28702 1/20 0.45
RXRG P48443 1/20 0.45
PDE7A Q13946 2/20 0.44
PDE7B Q9NP56 2/20 0.44
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
MAPT P10636 3/20 0.43
ALDH1A1 P00352 2/20 0.43
HPGD P15428 2/20 0.43
LMNA P02545 3/20 0.41
KDM4E B2RXH2 1/20 0.41
GLA P06280 1/20 0.41
GP6 Q9HCN6 1/20 0.41
NPC1 O15118 2/20 0.41
XBP1 P17861 2/20 0.41
HTT P42858 2/20 0.41
RAB9A P51151 2/20 0.41
PAX8 Q06710 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24702679 1.00 L3MBTL1 (0.46) L3MBTL1RXRARXRBRXRGPDE7A
SCHEMBL21661896 0.98 L3MBTL1 (0.47) L3MBTL1RXRARXRBRXRGPDE7A
SCHEMBL24622601 0.98 L3MBTL1 (0.47) L3MBTL1RXRARXRBRXRGPDE7A
SCHEMBL24795572 0.96 L3MBTL1 (0.44) L3MBTL1RXRARXRBRXRGPDE7A
SCHEMBL21661843 0.92 HSD17B1 (0.45) RXRARXRBRXRGPDE7APDE7B
SCHEMBL17563608 0.91 L3MBTL1 (0.54) L3MBTL1RXRARXRBRXRGMEN1
SCHEMBL25883662 0.91 L3MBTL1 (0.54) L3MBTL1RXRARXRBRXRGMEN1
SCHEMBL20152494 0.91 L3MBTL1 (0.54) L3MBTL1RXRARXRBRXRGMEN1
SCHEMBL23944865 0.88 MEN1 (0.49) L3MBTL1PDE7APDE7BMEN1KMT2A
SCHEMBL18472204 0.87 L3MBTL1 (0.45) L3MBTL1RXRARXRBRXRGPDE7A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200235306-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2020-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200235306-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME OR10J3, PIEZO1, ODC1 L3MBTL1 695/4885RXRA 3523/4885RXRB 3741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.