SCHEMBL222518

SCHEMBL222518

CC1CNC(=O)c2ccc3c(c2CC3C)C(=O)N1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36
NPC1 O15118 4/20 0.35
RAB9A P51151 4/20 0.35
CYP1A2 P05177 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
CYP2C19 P33261 1/20 0.35
HTR2A P28223 4/20 0.33
HTR2C P28335 4/20 0.33
HTR2B P41595 4/20 0.33
LMNA P02545 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TP53 P04637 1/20 0.33
HTT P42858 1/20 0.33
MKNK1 Q9BUB5 1/20 0.33
CDC7 O00311 2/20 0.33
ACHE P22303 2/20 0.33
LRRK2 Q5S007 1/20 0.32
CDK1 P06493 3/20 0.32
MAPKAPK2 P49137 3/20 0.32
MEN1 O00255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6678995 0.79 TSHR (0.41) TSHRNPC1RAB9ACYP1A2SMN1; SMN2
SCHEMBL23863601 0.68
SCHEMBL1756151 0.66 PARP1 (0.47) ALDH1A1ACHEPARP1
SCHEMBL30124448 0.65 SMN1; SMN2 (0.48) TSHRNPC1RAB9ACYP1A2SMN1; SMN2
SCHEMBL20612146 0.64 PARP10 (0.45) NPC1RAB9ACYP1A2SMN1; SMN2CYP2C19
SCHEMBL29624092 0.63 TSHR (0.49) TSHRNPC1RAB9ACYP1A2SMN1; SMN2
SCHEMBL7187432 0.60 MAOA (0.40) ACHE
SCHEMBL8178860 0.60 HPGD (0.42) SMN1; SMN2LMNAALDH1A1TP53HTT
SCHEMBL8178838 0.60 HPGD (0.42) SMN1; SMN2LMNAALDH1A1TP53HTT
SCHEMBL6200350 0.60 TSHR (0.45) TSHRNPC1RAB9ACYP1A2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0100146-B1 TACKIFIED CROSSLINKED ACRYLIC ADHESIVES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-08-27 EP claimed
EP-0100146-A1 Tackified crosslinked acrylic adhesives MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-02-08 EP claimed
US-4418120-A COATING WITH ACRYLIC ACID-ISOOCTYL ACRYLATE COPOLYMER, ROSIN AND ANTIOXIDANT, DESOLVENTIZATION, AND CROSSLINKING MINNESOTA MINING AND MANUFACTURING CO. (US) 1983-11-29 US claimed
EP-3337867-B1 AIR AND WATER BARRIER ARTICLE WITH POROUS LAYER AND LINER 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-04-10 EP disclosed
US-11654664-B2 Composite cooling film comprising a reflective nonporous organic polymeric layer and a UV-protective layer 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-05-23 US disclosed
US-20230019944-A1 Composite Cooling Film Comprising a Reflective Nonporous Organic Polymeric Layer and a UV-Protective Layer 3M INNOVATIVE PROPERTIES COMPANY 2023-01-19 US disclosed
US-11365328-B2 Air and water barrier article including inelastic porous layer 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-06-21 US disclosed
EP-4010184-A1 TAPE, ARTICLE INCLUDING TAPE AND COMPOSITE LAYER, AND RELATED METHODS 3M Innovative Properties Company (US) 2022-06-15 EP disclosed
WO-2022118246-A1 ENCAPSULATED FIRE RETARDANT AND RELATED COMPOSITIONS AND PROCESSES 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-06-09 WO disclosed
EP-2956517-B1 PRESSURE SENSITIVE ADHESIVE TAPE AND ARTICLES MADE THEREFROM 3M INNOVATIVE PROPERTIES CO (US) 2021-12-08 EP disclosed
US-11110689-B2 Pressure sensitive adhesive composition including ultraviolet light-absorbing oligomer 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-09-07 US disclosed
US-5141989-A Adhesion, shear strength, waterproof;(meth)acrylic ester, (meth)acrylic acid copolymer MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1992-08-25 US disclosed
EP-0213737-B1 PRESSURE-SENSITIVE ADHESIVE TAPE CONTAINING HYDROPHOBIC SILICA MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-09-05 EP disclosed
US-4749590-A ADDITION POLYMERIZATION, CROSSLINKING ACRYLIC MONOMERS; MIXING SILICA IN PRIOR TO REACTING MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-06-07 US disclosed
US-4726982-A ACRYLIC ACID COPOLYMER; ALKYL ESTER AND N-VINYL-LACTAM MONOMERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-02-23 US disclosed
US-4710536-A SHEAR STRENGTH AT ELEVATED TEMPERATURES IMPROVED MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-12-01 US disclosed
EP-0213737-A1 Pressure-sensitive adhesive tape containing hydrophobic silica MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-03-11 EP disclosed
EP-0100146-B1 TACKIFIED CROSSLINKED ACRYLIC ADHESIVES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-08-27 EP disclosed
EP-0100146-A1 Tackified crosslinked acrylic adhesives MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-02-08 EP disclosed
US-4418120-A COATING WITH ACRYLIC ACID-ISOOCTYL ACRYLATE COPOLYMER, ROSIN AND ANTIOXIDANT, DESOLVENTIZATION, AND CROSSLINKING MINNESOTA MINING AND MANUFACTURING CO. (US) 1983-11-29 US disclosed