Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25551709 | 1.00 | POLB (0.33) | POLBMAPK8ROCK2 | |
| SCHEMBL22254837 | 0.90 | MAPK8 (0.35) | POLBMAPK8 | |
| SCHEMBL22255004 | 0.88 | ROCK2 (0.38) | POLBMAPK8ROCK2 | |
| SCHEMBL25551399 | 0.88 | ROCK2 (0.38) | POLBMAPK8ROCK2 | |
| SCHEMBL22254816 | 0.87 | SIGMAR1 (0.30) | POLB | |
| SCHEMBL22254844 | 0.87 | SIGMAR1 (0.30) | POLB | |
| SCHEMBL25531949 | 0.87 | SIGMAR1 (0.30) | POLB | |
| SCHEMBL25547250 | 0.86 | ALDH1A1 (0.30) | POLBROCK2 | |
| SCHEMBL22254283 | 0.86 | ALDH1A1 (0.30) | POLBROCK2 | |
| SCHEMBL22254152 | 0.86 | ROCK2 (0.40) | POLBROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150385-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |