Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24195804 | 0.74 | — | — | |
| SCHEMBL69496 | 0.71 | ALDH1A1 (0.46) | ALDH1A1POLBMEN1KMT2AATM | |
| SCHEMBL18134201 | 0.71 | ALDH1A1 (0.46) | ALDH1A1POLBMEN1KMT2AATM | |
| SCHEMBL13992169 | 0.67 | ALDH1A1 (0.42) | ALDH1A1POLBMEN1KMT2AATM | |
| SCHEMBL713102 | 0.67 | SMN1; SMN2 (0.46) | ALDH1A1POLBMEN1KMT2AATM | |
| SCHEMBL1152835 | 0.67 | SMN1; SMN2 (0.42) | ALDH1A1POLBMEN1KMT2AATM | |
| SCHEMBL102472 | 0.67 | POLB (0.41) | ALDH1A1TSHRPOLBMEN1KMT2A | |
| SCHEMBL22014551 | 0.66 | KMT2A (0.33) | ALDH1A1TSHRMEN1KMT2AHSD17B10 | |
| SCHEMBL4759633 | 0.66 | POLB (0.43) | ALDH1A1POLBMEN1KMT2AATM | |
| SCHEMBL11470013 | 0.66 | ALDH1A1 (0.40) | ALDH1A1POLBMEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150385-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |