Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.36 |
| ▸ | CDK9 | P50750 | 5/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.36 |
| ▸ | CDK4 | P11802 | 2/20 | 0.36 |
| ▸ | CCND1 | P24385 | 2/20 | 0.36 |
| ▸ | CDK3 | Q00526 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22255193 | 1.00 | SLC6A4 (0.52) | SLC6A4ACACBCCNT1CDK9CCNE1 | |
| SCHEMBL22254879 | 1.00 | SLC6A4 (0.52) | SLC6A4ACACBCCNT1CDK9CCNE1 | |
| SCHEMBL25541864 | 0.88 | SLC6A4 (0.52) | SLC6A4ACACBCCNT1CDK9CCNE1 | |
| SCHEMBL25531150 | 0.85 | SLC6A4 (0.49) | SLC6A4ACACBCCNT1CDK9CCNE1 | |
| SCHEMBL25541896 | 0.85 | SLC6A4 (0.49) | SLC6A4ACACBCCNT1CDK9CCNE1 | |
| SCHEMBL25541881 | 0.85 | SLC6A4 (0.49) | SLC6A4ACACBCCNT1CDK9CCNE1 | |
| SCHEMBL12404706 | 0.80 | SLC6A4 (0.59) | SLC6A4ACACBSIGMAR1MEN1KMT2A | |
| SCHEMBL25541894 | 0.75 | SLC6A4 (0.55) | SLC6A4ACACBSIGMAR1TRPV1 | |
| SCHEMBL22255188 | 0.75 | SIGMAR1 (0.53) | SLC6A4ACACBSIGMAR1SMN1; SMN2CYP1A2 | |
| SCHEMBL22255184 | 0.75 | SIGMAR1 (0.53) | SLC6A4ACACBSIGMAR1SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150385-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |