Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.53 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22255188 | 1.00 | SIGMAR1 (0.53) | SIGMAR1ACACBSLC6A4SMN1; SMN2HTT | |
| SCHEMBL22254880 | 0.80 | SIGMAR1 (0.54) | SIGMAR1ACACBSLC6A4SMN1; SMN2HTT | |
| SCHEMBL12404709 | 0.80 | SIGMAR1 (0.62) | SIGMAR1ACACBSLC6A4SMN1; SMN2HTT | |
| SCHEMBL22254877 | 0.75 | SLC6A4 (0.52) | SIGMAR1ACACBSLC6A4SMN1; SMN2CYP1A2 | |
| SCHEMBL22254879 | 0.75 | SLC6A4 (0.52) | SIGMAR1ACACBSLC6A4SMN1; SMN2CYP1A2 | |
| SCHEMBL22255193 | 0.75 | SLC6A4 (0.52) | SIGMAR1ACACBSLC6A4SMN1; SMN2CYP1A2 | |
| SCHEMBL22255190 | 0.72 | SLC6A4 (0.38) | SIGMAR1SLC6A4CYP1A2CYP2D6TSHR | |
| SCHEMBL22255182 | 0.72 | SLC6A4 (0.38) | SIGMAR1SLC6A4CYP1A2CYP2D6TSHR | |
| SCHEMBL19012043 | 0.71 | SIGMAR1 (0.68) | SIGMAR1ACACBSLC6A4CYP1A2CYP3A4 | |
| SCHEMBL11410303 | 0.70 | SIGMAR1 (0.49) | SIGMAR1ACACBSLC6A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150385-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |