Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | ACACB | O00763 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | EBP | Q15125 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | CDK3 | Q00526 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25541881 | 1.00 | SLC6A4 (0.49) | SLC6A4ACACBTP53TSHRSIGMAR1 | |
| SCHEMBL25541896 | 1.00 | SLC6A4 (0.49) | SLC6A4ACACBTP53TSHRSIGMAR1 | |
| SCHEMBL25541894 | 0.92 | SLC6A4 (0.55) | SLC6A4ACACBTP53TSHRSIGMAR1 | |
| SCHEMBL25531111 | 0.85 | SLC6A4 (0.50) | SLC6A4ACACBTP53TSHRSIGMAR1 | |
| SCHEMBL25541864 | 0.85 | SLC6A4 (0.52) | SLC6A4ACACBSIGMAR1CCNT1CDK4 | |
| SCHEMBL22255193 | 0.85 | SLC6A4 (0.52) | SLC6A4ACACBSIGMAR1TRPV1KDM1A | |
| SCHEMBL22254879 | 0.85 | SLC6A4 (0.52) | SLC6A4ACACBSIGMAR1TRPV1KDM1A | |
| SCHEMBL22254877 | 0.85 | SLC6A4 (0.52) | SLC6A4ACACBSIGMAR1TRPV1KDM1A | |
| SCHEMBL25541899 | 0.81 | SLC6A4 (0.55) | SLC6A4ACACBTP53TSHRSIGMAR1 | |
| SCHEMBL25541866 | 0.81 | SLC6A4 (0.52) | SLC6A4ACACBTP53TSHRSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | MPO, NISCH, RPN2 | SLC6A4 3119/4885ACACB 2485/4885TP53 4099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.