Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | FAP | Q12884 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22254882 | 0.89 | SLC6A4 (0.33) | SLC6A4SLC6A2OPRK1ADRA2BADRA2C | |
| SCHEMBL25541883 | 0.85 | TP53 (0.39) | SLC6A4KCNH2DPP4FAPDPP8 | |
| SCHEMBL25531098 | 0.85 | TP53 (0.39) | SLC6A4KCNH2DPP4FAPDPP8 | |
| SCHEMBL25541902 | 0.76 | TP53 (0.41) | SLC6A4ADRA2BADRA2CADRA1AKCNH2 | |
| SCHEMBL25532170 | 0.74 | ROCK2 (0.37) | — | |
| SCHEMBL25532177 | 0.74 | ROCK2 (0.37) | — | |
| SCHEMBL22255182 | 0.72 | SLC6A4 (0.38) | SLC6A4SLC6A2OPRK1ADRA2BADRA2C | |
| SCHEMBL22255190 | 0.72 | SLC6A4 (0.38) | SLC6A4SLC6A2OPRK1ADRA2BADRA2C | |
| SCHEMBL22254879 | 0.70 | SLC6A4 (0.52) | SLC6A4 | |
| SCHEMBL22254877 | 0.70 | SLC6A4 (0.52) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150385-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |