Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.52 |
| ▸ | SLC7A5 | Q01650 | 5/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | GRB2 | P62993 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | TPH1 | P17752 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7454762 | 1.00 | ITGB3 (0.54) | ITGB3ITGA2BPTPN1SLC7A5PTGS1 | |
| SCHEMBL16355748 | 0.89 | PTPN1 (0.48) | ITGB3ITGA2BPTPN1SLC7A5HDAC8 | |
| SCHEMBL7298611 | 0.87 | PTPN1 (0.47) | ITGB3ITGA2BPTPN1HDAC8PTGS2 | |
| SCHEMBL8763598 | 0.87 | PTPN1 (0.47) | ITGB3ITGA2BPTPN1HDAC8PTGS2 | |
| SCHEMBL13141375 | 0.86 | PTPN1 (0.50) | ITGB3ITGA2BPTPN1HDAC8 | |
| SCHEMBL12042755 | 0.85 | PTPN1 (0.52) | ITGB3ITGA2BPTPN1HDAC8 | |
| SCHEMBL7099897 | 0.85 | PTPN1 (0.52) | ITGB3ITGA2BPTPN1HDAC8 | |
| SCHEMBL21689965 | 0.85 | ITGB3 (0.58) | ITGB3ITGA2BPTPN1SLC7A5PTGS1 | |
| SCHEMBL21690036 | 0.84 | SLC7A5 (0.57) | ITGB3ITGA2BPTPN1SLC7A5PTGS1 | |
| SCHEMBL14257829 | 0.84 | SLC7A5 (0.57) | ITGB3ITGA2BPTPN1SLC7A5PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159549-A | Immunomodulators | 百时美施贵宝公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-118076623-A | Macrocyclic immunomodulators | 百时美施贵宝公司 | 2024-05-24 | — | — | CN | disclosed |
| EP-4370530-A1 | MACROCYCLIC IMMUNOMODULATORS | Bristol-Myers Squibb Company (US) | 2024-05-22 | — | — | EP | disclosed |
| CN-117940445-A | Macrocyclic immunomodulators | 百时美施贵宝公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-117157306-A | Immunomodulators | 百时美施贵宝公司 | 2023-12-01 | — | — | CN | disclosed |
| WO-2023288213-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-01-19 | — | — | WO | disclosed |
| US-20200230133-A1 | Discrete PEG Constructs | EqIP, LLC (US) | 2020-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200230133-A1 | Discrete PEG Constructs | MUC1, EGFR, LNPEP | ITGB3 1886/4885ITGA2B 1586/4885PTPN1 2137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.