SCHEMBL22256503

SCHEMBL22256503

Fc1cc(F)cc(C2CCON2)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22233087 1.00
SCHEMBL21783593 1.00
Hydrochloric Acid SCHEMBL30339018 0.98
SCHEMBL25819471 0.89
SCHEMBL25189077 0.88 TRPM5 (0.35)
SCHEMBL31087334 0.88 TRPM5 (0.35)
SCHEMBL27054181 0.88 EPAS1 (0.36)
SCHEMBL22444805 0.88 TRPM5 (0.35)
SCHEMBL22444804 0.88 TRPM5 (0.35)
Hydrochloric Acid SCHEMBL30020455 0.86 EPAS1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709722-A1 ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF GENZYME CORPORATION (US) 2026-03-18 EP disclosed
EP-4709716-A1 ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF GENZYME CORPORATION (US) 2026-03-18 EP disclosed
US-12534457-B2 Heteroaryl derivative compounds, and uses thereof VORONOI INC. (KR) 2026-01-27 US disclosed
US-12528799-B2 Heteroaryl derivative compounds, and uses thereof VORONOI INC. (KR) 2026-01-20 US disclosed
US-20250368635-A1 HETEROARYL DERIVATIVE COMPOUND, AND USES THEREOF VORONOI, INC. (KR) 2025-12-04 US disclosed
EP-4631507-A2 HETEROARYL DERIVATIVE, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE COMPONENT Voronoi Inc. (KR) 2025-10-15 EP disclosed
EP-4619403-A1 HETEROARYL DERIVATIVE COMPOUND, AND USES THEREOF Voronoi, Inc. (KR) 2025-09-24 EP disclosed
EP-3943491-B1 HETEROARYL DERIVATIVE, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE COMPONENT VORONOI INC (KR) 2025-06-18 EP disclosed
US-20250019373-A1 ARYL OR HETEROARYL DERIVATIVE, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF KINASE-RELATED DISEASES VORONOI INC. (KR) 2025-01-16 US disclosed
US-12157730-B2 Heteroaryl derivative, method for producing same, and pharmaceutical composition comprising same as effective component VORONOI INC. (KR) 2024-12-03 US disclosed
CN-114605400-A Heteroaryl derivatives, process for preparing the same, and pharmaceutical composition containing the same as active ingredient 株式会社沃若诺伊 2022-06-10 CN disclosed
US-20220162203-A1 HETEROARYL DERIVATIVE, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE COMPONENT VORONOI INC. (KR) 2022-05-26 US disclosed
WO-2022060196-A1 HETEROARYL DERIVATIVE, METHOD FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT 보로노이바이오 주식회사 2022-03-24 WO disclosed
EP-3971190-A1 HETEROCYCLE-FUSED PYRIMIDINE DERIVATIVE AND USE THEREOF Voronoi Inc. (KR) 2022-03-23 EP disclosed
CN-113993866-A Heteroaryl derivatives, process for preparing the same, and pharmaceutical composition containing the same as active ingredient 株式会社沃若诺伊 2022-01-28 CN disclosed
EP-3943491-A1 HETEROARYL DERIVATIVE, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE COMPONENT Voronoi Inc. (KR) 2022-01-26 EP disclosed
EP-3732176-A1 HETEROCYCLIC AMIDES AS KINASE INHIBITORS GlaxoSmithKline Intellectual Property Development Ltd (GB) 2020-11-04 EP disclosed
CN-111741957-A Heterocyclic amides as kinase inhibitors 葛兰素史密斯克莱知识产权发展有限公司 2020-10-02 CN disclosed
WO-2020190119-A1 HETEROARYL DERIVATIVE, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE COMPONENT 주식회사 보로노이 2020-09-24 WO disclosed
WO-2020149553-A1 ARYL OR HETEROARYL DERIVATIVE, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR TREATMENT OF KINASE-RELATED DISEASE 주식회사 보로노이 2020-07-23 WO disclosed