⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22233087 | 0.89 | — | — | |
| SCHEMBL21783593 | 0.89 | — | — | |
| SCHEMBL22256503 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL30339018 | 0.87 | — | — | |
| SCHEMBL25189077 | 0.81 | TRPM5 (0.35) | — | |
| SCHEMBL22444805 | 0.81 | TRPM5 (0.35) | — | |
| SCHEMBL22444804 | 0.81 | TRPM5 (0.35) | — | |
| SCHEMBL31087334 | 0.81 | TRPM5 (0.35) | — | |
| SCHEMBL27054181 | 0.81 | EPAS1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL30020455 | 0.80 | EPAS1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219937-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | SANOFI (FR) | 2023-07-13 | — | — | US | disclosed |