Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM5 | Q9NZQ8 | 7/20 | 0.35 |
| ▸ | TRPM4 | Q8TD43 | 2/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31087334 | 1.00 | TRPM5 (0.35) | TRPM5TRPM4RIPK1 | |
| SCHEMBL25189077 | 1.00 | TRPM5 (0.35) | TRPM5TRPM4RIPK1 | |
| SCHEMBL22444805 | 1.00 | TRPM5 (0.35) | TRPM5TRPM4RIPK1 | |
| SCHEMBL21783593 | 0.88 | — | — | |
| SCHEMBL22233087 | 0.88 | — | — | |
| SCHEMBL22256503 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL30339018 | 0.86 | — | — | |
| SCHEMBL25819471 | 0.81 | — | — | |
| SCHEMBL27054181 | 0.80 | EPAS1 (0.36) | — | |
| SCHEMBL29433917 | 0.80 | NOTUM (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4631507-A2 | HETEROARYL DERIVATIVE, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE COMPONENT | Voronoi Inc. (KR) | 2025-10-15 | — | — | EP | disclosed |
| EP-3943491-B1 | HETEROARYL DERIVATIVE, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE COMPONENT | VORONOI INC (KR) | 2025-06-18 | — | — | EP | disclosed |
| US-12157730-B2 | Heteroaryl derivative, method for producing same, and pharmaceutical composition comprising same as effective component | VORONOI INC. (KR) | 2024-12-03 | — | — | US | disclosed |
| US-12152021-B2 | Heteroaryl derivative, method for producing same, and pharmaceutical composition comprising same as effective component | VORONOI INC. (KR) | 2024-11-26 | — | — | US | disclosed |
| CN-114605400-B | Heteroaryl derivatives, process for preparing the same, and pharmaceutical compositions containing the same as active ingredient | 株式会社沃若诺伊 | 2024-09-10 | — | — | CN | disclosed |
| US-20240150337-A1 | HETEROARYL DERIVATIVE, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE COMPONENT | VORONOIBIO INC. (KR) | 2024-05-09 | — | — | US | disclosed |
| CN-115838369-A | Heteroaryl derivatives, process for preparing the same, and pharmaceutical composition containing the same as active ingredient | 株式会社沃若诺伊 | 2023-03-24 | — | — | CN | disclosed |
| CN-113993866-B | Heteroaryl derivatives, process for preparing the same, and pharmaceutical composition containing the same as active ingredient | 株式会社沃若诺伊 | 2022-10-28 | — | — | CN | disclosed |
| US-11466000-B2 | Heteroaryl derivative, method for producing same, and pharmaceutical composition comprising same as effective component | VORONOI INC. (KR) | 2022-10-11 | — | — | US | disclosed |
| US-20220289733-A1 | HETEROARYL DERIVATIVE, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE COMPONENT | VORONOI INC. (KR) | 2022-09-15 | — | — | US | disclosed |
| CN-114605400-A | Heteroaryl derivatives, process for preparing the same, and pharmaceutical composition containing the same as active ingredient | 株式会社沃若诺伊 | 2022-06-10 | — | — | CN | disclosed |
| US-20220162203-A1 | HETEROARYL DERIVATIVE, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE COMPONENT | VORONOI INC. (KR) | 2022-05-26 | — | — | US | disclosed |
| CN-113993866-A | Heteroaryl derivatives, process for preparing the same, and pharmaceutical composition containing the same as active ingredient | 株式会社沃若诺伊 | 2022-01-28 | — | — | CN | disclosed |
| EP-3943491-A1 | HETEROARYL DERIVATIVE, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE COMPONENT | Voronoi Inc. (KR) | 2022-01-26 | — | — | EP | disclosed |
| WO-2020190119-A1 | HETEROARYL DERIVATIVE, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE COMPONENT | 주식회사 보로노이 | 2020-09-24 | — | — | WO | disclosed |
| WO-2020190119-A1 | HETEROARYL DERIVATIVE, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE COMPONENT | 주식회사 보로노이 | 2020-09-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12157730-B2 | Heteroaryl derivative, method for producing same, and pharmaceutical composition comprising same as effective component | ERBB4, ERBB2, EGFR | TRPM5 2534/4885TRPM4 806/4885RIPK1 4240/4885 |
| US-20220289733-A1 | HETEROARYL DERIVATIVE, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE COMPONENT | ERBB4, ERBB2, EGFR | TRPM5 2534/4885TRPM4 806/4885RIPK1 4240/4885 |
| US-20220162203-A1 | HETEROARYL DERIVATIVE, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE COMPONENT | ERBB4, ERBB2, EGFR | TRPM5 2534/4885TRPM4 806/4885RIPK1 4240/4885 |
| US-11466000-B2 | Heteroaryl derivative, method for producing same, and pharmaceutical composition comprising same as effective component | ERBB4, ERBB2, EGFR | TRPM5 2534/4885TRPM4 806/4885RIPK1 4240/4885 |
| US-12152021-B2 | Heteroaryl derivative, method for producing same, and pharmaceutical composition comprising same as effective component | ERBB4, ERBB2, EGFR | TRPM5 2534/4885TRPM4 806/4885RIPK1 4240/4885 |
| US-20240150337-A1 | HETEROARYL DERIVATIVE, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE COMPONENT | ERBB4, ERBB2, EGFR | TRPM5 2534/4885TRPM4 806/4885RIPK1 4240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.