SCHEMBL2225753

SCHEMBL2225753

O=C1CCCC/C1=C/O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2225759 1.00
SCHEMBL4105554 1.00
SCHEMBL1843217 0.97 ALDH1A1 (0.41)
SCHEMBL4299474 0.97 ALDH1A1 (0.41)
SCHEMBL5241106 0.97 ALDH1A1 (0.41)
SCHEMBL2945718 0.97 ALDH1A1 (0.41)
SCHEMBL1843218 0.97 ALDH1A1 (0.41)
SCHEMBL5583266 0.97 ALDH1A1 (0.41)
SCHEMBL4299469 0.97 ALDH1A1 (0.41)
SCHEMBL17585991 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0007582-B1 COMPOSITIONS AND PROCESS FOR REINFORCING, MODIFYING OR IMPROVING THE ORGANOLEPTIC PROPERTIES OF TOBACCO PRODUCTS AND COMPOUNDS USEFUL THEREFOR L. GIVAUDAN &amp; CIE Société Anonyme (CH) 1981-11-25 EP claimed
EP-0007582-A2 Compositions and process for reinforcing, modifying or improving the organoleptic properties of tobacco products and compounds useful therefor L. GIVAUDAN &amp; CIE Société Anonyme (CH) 1980-02-06 EP claimed
US-4183363-A Tobacco compositions flavored with 2-hydroxymethylenecyclohexanones GIVAUDAN CORPORATION (US) 1980-01-15 US claimed
US-20250353852-A1 COMPOUNDS AND COMPOSITIONS THAT INHIBIT PIKFYVE KINETA INC (US) 2025-11-20 US disclosed
EP-4444316-A1 COMPOUNDS AND COMPOSITIONS THAT INHIBIT PIKFYVE Kineta, Inc. (US) 2024-10-16 EP disclosed
WO-2023107557-A1 COMPOUNDS AND COMPOSITIONS THAT INHIBIT PIKFYVE Kineta, Inc. (US) 2023-06-15 WO disclosed
WO-2023107557-A1 COMPOUNDS AND COMPOSITIONS THAT INHIBIT PIKFYVE Kineta, Inc. (US) 2023-06-15 WO disclosed
WO-2023088388-A1 TETRAHYDROCARBAZOLE COMPOUND, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF 杭州拿因生物科技有限责任公司 2023-05-25 WO disclosed
EP-3912977-A1 GLUCOSYLCERAMIDE SYNTHASE INHIBITORS FOR THE TREATMENT OF DISEASES BioMarin Pharmaceutical Inc. (US) 2021-11-24 EP disclosed
US-11084933-B2 Dye compound and photopolymer composition LG CHEM, LTD. (KR) 2021-08-10 US disclosed
EP-3046920-B1 GLUCOSYLCERAMIDE SYNTHASE INHIBITORS FOR THE TREATMENT OF DISEASES BIOMARIN PHARM INC (US) 2021-08-04 EP disclosed
EP-0007582-A2 Compositions and process for reinforcing, modifying or improving the organoleptic properties of tobacco products and compounds useful therefor L. GIVAUDAN &amp; CIE Société Anonyme (CH) 1980-02-06 EP disclosed
US-4183363-A Tobacco compositions flavored with 2-hydroxymethylenecyclohexanones GIVAUDAN CORPORATION (US) 1980-01-15 US disclosed
US-4183363-A Tobacco compositions flavored with 2-hydroxymethylenecyclohexanones GIVAUDAN CORPORATION (US) 1980-01-15 US disclosed
US-4183363-A Tobacco compositions flavored with 2-hydroxymethylenecyclohexanones GIVAUDAN CORPORATION (US) 1980-01-15 US disclosed
US-4100352-A Cyclohexanone-5,6-benzo analogues of prostaglandin MILES LABORATORIES, INC. (US) 1978-07-11 US disclosed
US-4100353-A 5,6-Benza analogues of prostaglandin F MILES LABORATORIES, INC. (US) 1978-07-11 US disclosed
US-4100185-A Cyclohexanone 5,6-benzo analogues of prostaglandin E MILES LABORATORIES, INC. (US) 1978-07-11 US disclosed
US-4097516-A 5,6-Benzo analogues of prostaglandin E MILES LABORATORIES, INC. (US) 1978-06-27 US disclosed
US-4096336-A OXYTOCICS, ANTIULCER, BRONCHODILATION, ANTICOAGULANT, HYPOTENSIVE MILES LABORATORIES, INC. (US) 1978-06-20 US disclosed