Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1843218 | 1.00 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTSMN1; SMN2KMT2A | |
| SCHEMBL2945718 | 1.00 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTSMN1; SMN2KMT2A | |
| SCHEMBL5241106 | 1.00 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTSMN1; SMN2KMT2A | |
| SCHEMBL1843217 | 1.00 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTSMN1; SMN2KMT2A | |
| SCHEMBL4105554 | 0.97 | — | — | |
| SCHEMBL2225753 | 0.97 | — | — | |
| SCHEMBL2225759 | 0.97 | — | — | |
| SCHEMBL4299474 | 0.95 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTSMN1; SMN2KMT2A | |
| SCHEMBL4299469 | 0.95 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTSMN1; SMN2KMT2A | |
| SCHEMBL4154668 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070254877-A1 | Indole Derivative and Use for Treatment of Cancer | TAKADA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-11-01 | — | — | US | disclosed |
| US-20070254877-A1 | Indole Derivative and Use for Treatment of Cancer | TAKADA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-11-01 | — | — | US | disclosed |
| US-20070254877-A1 | Indole Derivative and Use for Treatment of Cancer | TAKADA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-11-01 | — | — | US | disclosed |
| US-4238623-A | 5,6-Benzo analogues of prostaglandin | MILES LABORATORIES, INC. (US) | 1980-12-09 | — | — | US | disclosed |
| US-4100352-A | Cyclohexanone-5,6-benzo analogues of prostaglandin | MILES LABORATORIES, INC. (US) | 1978-07-11 | — | — | US | disclosed |
| US-4100353-A | 5,6-Benza analogues of prostaglandin F | MILES LABORATORIES, INC. (US) | 1978-07-11 | — | — | US | disclosed |
| US-4100185-A | Cyclohexanone 5,6-benzo analogues of prostaglandin E | MILES LABORATORIES, INC. (US) | 1978-07-11 | — | — | US | disclosed |
| US-4097516-A | 5,6-Benzo analogues of prostaglandin E | MILES LABORATORIES, INC. (US) | 1978-06-27 | — | — | US | disclosed |
| US-4096336-A | OXYTOCICS, ANTIULCER, BRONCHODILATION, ANTICOAGULANT, HYPOTENSIVE | MILES LABORATORIES, INC. (US) | 1978-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254877-A1 | Indole Derivative and Use for Treatment of Cancer | IGF1R, KDR, ERBB2 | ALDH1A1 1181/4885KDM4E 1419/4885MAPT 4824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.