SCHEMBL2225759

SCHEMBL2225759

O=C1CCCCC1=CO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4105554 1.00
SCHEMBL2225753 1.00
SCHEMBL1843217 0.97 ALDH1A1 (0.41)
SCHEMBL4299474 0.97 ALDH1A1 (0.41)
SCHEMBL5241106 0.97 ALDH1A1 (0.41)
SCHEMBL2945718 0.97 ALDH1A1 (0.41)
SCHEMBL1843218 0.97 ALDH1A1 (0.41)
SCHEMBL5583266 0.97 ALDH1A1 (0.41)
SCHEMBL4299469 0.97 ALDH1A1 (0.41)
SCHEMBL17585991 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0007582-B1 COMPOSITIONS AND PROCESS FOR REINFORCING, MODIFYING OR IMPROVING THE ORGANOLEPTIC PROPERTIES OF TOBACCO PRODUCTS AND COMPOUNDS USEFUL THEREFOR L. GIVAUDAN &amp; CIE Société Anonyme (CH) 1981-11-25 EP claimed
EP-0007582-A2 Compositions and process for reinforcing, modifying or improving the organoleptic properties of tobacco products and compounds useful therefor L. GIVAUDAN &amp; CIE Société Anonyme (CH) 1980-02-06 EP claimed
US-4183363-A Tobacco compositions flavored with 2-hydroxymethylenecyclohexanones GIVAUDAN CORPORATION (US) 1980-01-15 US claimed
US-20250353852-A1 COMPOUNDS AND COMPOSITIONS THAT INHIBIT PIKFYVE KINETA INC (US) 2025-11-20 US disclosed
EP-4444316-A1 COMPOUNDS AND COMPOSITIONS THAT INHIBIT PIKFYVE Kineta, Inc. (US) 2024-10-16 EP disclosed
WO-2023112056-A1 NOVEL SUBSTITUTED FUSED BICYCLIC PYRIDINE CARBOXAMIDE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI PI INDUSTRIES LTD. (IN) 2023-06-22 WO disclosed
WO-2023107557-A1 COMPOUNDS AND COMPOSITIONS THAT INHIBIT PIKFYVE Kineta, Inc. (US) 2023-06-15 WO disclosed
CN-105531252-B Process for the preparation of β -cyclolavandulal and derivatives thereof 信越化学工业株式会社 2018-01-09 CN disclosed
EP-2526092-B1 AMINO HETEROARYL COMPOUNDS AS BETA-SECRETASE MODULATORS AND METHODS OF USE AMGEN INC (US) 2014-08-06 EP disclosed
US-8735384-B2 Amino heteroaryl compounds as beta-secretase modulators and methods of use AMGEN INC. (US) 2014-05-27 US disclosed
US-20130040931-A1 Amino Heteroaryl Compounds as Beta-Secretase Modulators and Methods of Use AMGEN INC. (US) 2013-02-14 US disclosed
US-4183363-A Tobacco compositions flavored with 2-hydroxymethylenecyclohexanones GIVAUDAN CORPORATION (US) 1980-01-15 US disclosed
US-4183363-A Tobacco compositions flavored with 2-hydroxymethylenecyclohexanones GIVAUDAN CORPORATION (US) 1980-01-15 US disclosed
US-4183363-A Tobacco compositions flavored with 2-hydroxymethylenecyclohexanones GIVAUDAN CORPORATION (US) 1980-01-15 US disclosed
US-4100352-A Cyclohexanone-5,6-benzo analogues of prostaglandin MILES LABORATORIES, INC. (US) 1978-07-11 US disclosed
US-4100353-A 5,6-Benza analogues of prostaglandin F MILES LABORATORIES, INC. (US) 1978-07-11 US disclosed
US-4100185-A Cyclohexanone 5,6-benzo analogues of prostaglandin E MILES LABORATORIES, INC. (US) 1978-07-11 US disclosed
US-4097516-A 5,6-Benzo analogues of prostaglandin E MILES LABORATORIES, INC. (US) 1978-06-27 US disclosed
US-4096336-A OXYTOCICS, ANTIULCER, BRONCHODILATION, ANTICOAGULANT, HYPOTENSIVE MILES LABORATORIES, INC. (US) 1978-06-20 US disclosed
US-3957817-A BRIGHTENERS BAYER AKTIENGESELLSCHAFT (DT) 1976-05-18 US disclosed