Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | CPA1 | P15085 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL222578 | 1.00 | CNR1 (0.45) | CNR1CPA1ALDH1A1CYP2C19TDP1 | |
| SCHEMBL221353 | 0.86 | TDP1 (0.47) | CPA1ALDH1A1CYP2C19TDP1L3MBTL1 | |
| SCHEMBL221352 | 0.86 | TDP1 (0.47) | CPA1ALDH1A1CYP2C19TDP1L3MBTL1 | |
| SCHEMBL6249908 | 0.80 | CPA1 (0.46) | CPA1ALDH1A1CYP2C19TDP1L3MBTL1 | |
| SCHEMBL220114 | 0.80 | CNR1 (0.43) | CNR1CPA1ALDH1A1CYP2C19LMNA | |
| SCHEMBL221213 | 0.80 | LMNA (0.43) | CNR1CPA1ALDH1A1CYP2C19TDP1 | |
| SCHEMBL221507 | 0.80 | LMNA (0.43) | CPA1ALDH1A1CYP2C19TDP1L3MBTL1 | |
| SCHEMBL221108 | 0.80 | ALDH1A1 (0.53) | CNR1ALDH1A1TDP1LMNACES2 | |
| SCHEMBL221212 | 0.80 | LMNA (0.43) | CNR1CPA1ALDH1A1CYP2C19TDP1 | |
| SCHEMBL220113 | 0.80 | CNR1 (0.43) | CNR1CPA1ALDH1A1CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940938-B2 | Michael reaction with recovery of the catalyst | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2015-01-27 | — | — | US | disclosed |
| US-20120004424-A1 | MICHAEL REACTION WITH RECOVERY OF THE CATALYST | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004424-A1 | MICHAEL REACTION WITH RECOVERY OF THE CATALYST | CYP2E1, CYP11B2, CYP11B1 | CNR1 1751/4885CPA1 3043/4885ALDH1A1 118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.