SCHEMBL22258684

SCHEMBL22258684

Clc1nc(-c2ccccc2)c2ccc3sc4ccc5ccccc5c4c3c2n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.41
ALDH1A1 P00352 4/20 0.41
KDM4E B2RXH2 4/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
HPGD P15428 2/20 0.41
GLA P06280 1/20 0.41
MAPT P10636 5/20 0.39
CYP1A1 P04798 3/20 0.35
CYP1B1 Q16678 3/20 0.35
KMT2A Q03164 4/20 0.35
OPRK1 P41145 1/20 0.35
CYP1A2 P05177 2/20 0.34
RECQL P46063 2/20 0.33
NUDT1 P36639 2/20 0.33
NQO1 P15559 1/20 0.33
NQO2 P16083 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
L3MBTL1 Q9Y468 3/20 0.32
MEN1 O00255 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22258673 0.90 CYP1A1 (0.41) LMNAALDH1A1KDM4ESMN1; SMN2HPGD
SCHEMBL22258685 0.89 CYP1A1 (0.36) LMNAALDH1A1KDM4ESMN1; SMN2HPGD
SCHEMBL19758804 0.86 KDM4E (0.42) LMNAALDH1A1KDM4ESMN1; SMN2HPGD
SCHEMBL22258720 0.86 CYP1A1 (0.34) LMNAALDH1A1SMN1; SMN2HPGDMAPT
SCHEMBL22258682 0.83 MAPT (0.37) LMNAALDH1A1HPGDMAPTCYP1A1
SCHEMBL22258679 0.83 KDM4E (0.41) LMNAALDH1A1KDM4ESMN1; SMN2HPGD
SCHEMBL22259017 0.83 MEN1 (0.42) LMNAALDH1A1KDM4ESMN1; SMN2HPGD
SCHEMBL17305861 0.83 ALDH1A1 (0.41) LMNAALDH1A1KDM4ESMN1; SMN2HPGD
SCHEMBL17367230 0.81 ALDH1A1 (0.52) LMNAALDH1A1KDM4ESMN1; SMN2HPGD
SCHEMBL29464956 0.81 ALDH1A1 (0.52) LMNAALDH1A1KDM4ESMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11211568-B2 Compound for organic electroluminescence device using the same LUMINESCENCE TECHNOLOGY CORP. (TW) 2021-12-28 US disclosed
US-20200235311-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2020-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11211568-B2 Compound for organic electroluminescence device using the same OR10J3, PIEZO1, ICMT LMNA 1881/4885ALDH1A1 353/4885KDM4E 1352/4885
US-20200235311-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME OR10J3, PIEZO1, ICMT LMNA 1881/4885ALDH1A1 353/4885KDM4E 1352/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.