Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22258956 | 0.83 | ROCK2 (0.44) | DYRK1APIM1 | |
| SCHEMBL22258664 | 0.80 | CHEK1 (0.57) | CHEK1 | |
| SCHEMBL13375184 | 0.77 | LMNA (0.42) | GABRA5PDE4BCNR2 | |
| SCHEMBL15660637 | 0.77 | EIF4E (0.47) | GABRA5PIM1CNR2CHEK1 | |
| SCHEMBL13374017 | 0.74 | KDM1A (0.40) | PDE4BCNR2CHEK1 | |
| SCHEMBL13373952 | 0.74 | HPGD (0.38) | DYRK1APIK3C3PDE4BCNR2CHEK1 | |
| SCHEMBL15705201 | 0.74 | SMN1; SMN2 (0.56) | CHEK1 | |
| SCHEMBL22258961 | 0.72 | CNR1 (0.47) | CNR2 | |
| SCHEMBL15661172 | 0.71 | HPGD (0.37) | PIM1PDE4BCHEK1 | |
| SCHEMBL15660027 | 0.71 | ALDH1A1 (0.39) | PIM1PDE4BCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150545-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF THE WNT/B-CATENIN SIGNALING PATHWAY | SAMUMED, LLC (US) | 2020-07-23 | — | — | WO | disclosed |