Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.63 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.63 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.63 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.63 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22259538 | 0.91 | MAPK1 (0.63) | MAPK1GABRA1GABRB2CYP1A2CYP3A4 | |
| SCHEMBL22259537 | 0.89 | GABRA1 (0.75) | MAPK1GABRA1GABRB2CYP1A2CYP3A4 | |
| SCHEMBL22756042 | 0.88 | MAPK1 (0.72) | MAPK1GABRA1GABRB2CYP1A2CYP3A4 | |
| SCHEMBL22696701 | 0.88 | MAPK1 (0.72) | MAPK1GABRA1GABRB2CYP1A2CYP3A4 | |
| SCHEMBL15125296 | 0.87 | MAPK1 (0.72) | MAPK1GABRA1GABRB2CYP1A2CYP3A4 | |
| Metomidate SCHEMBL491910 | 0.86 | MAPK1 (0.97) | MAPK1GABRA1GABRB2CYP1A2CYP3A4 | |
| Metomidate SCHEMBL4377172 | 0.86 | MAPK1 (0.97) | MAPK1GABRA1GABRB2CYP1A2CYP3A4 | |
| SCHEMBL5103242 | 0.85 | MAPK1 (0.69) | MAPK1GABRA1GABRB2CYP1A2CYP3A4 | |
| Metomidate SCHEMBL1845324 | 0.85 | MAPK1 (1.00) | MAPK1GABRA1GABRB2CYP1A2CYP3A4 | |
| SCHEMBL22696793 | 0.84 | MAPK1 (0.67) | MAPK1GABRA1GABRB2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3587403-B1 | N-SUBSTITUTED IMIDAZOLE CARBOXYLATE COMPOUND, PREPARATION METHOD AND USE | WEST CHINA HOSPITAL SICHUAN UNIV (CN) | 2023-08-23 | — | — | EP | disclosed |
| US-11208385-B2 | N-substituted imidazole carboxylate compound, preparation method and use | WEST CHINA HOSPITAL, SICHUAN UNIVERSITY (CN) | 2021-12-28 | — | — | US | disclosed |
| US-20200231546-A1 | N-SUBSTITUTED IMIDAZOLE CARBOXYLATE COMPOUND, PREPARATION METHOD AND USE | WEST CHINA HOSPITAL, SICHUAN UNIVERSITY (CN) | 2020-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11208385-B2 | N-substituted imidazole carboxylate compound, preparation method and use | NR3C1, CYP2E1, CYP3A5 | MAPK1 988/4885GABRA1 25/4885GABRB2 114/4885 |
| US-20200231546-A1 | N-SUBSTITUTED IMIDAZOLE CARBOXYLATE COMPOUND, PREPARATION METHOD AND USE | CHRM1, CYP2C18, CYP2E1 | MAPK1 1819/4885GABRA1 11/4885GABRB2 53/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.