Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 7/20 | 0.77 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.77 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.77 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.77 |
| ▸ | LMNA | P02545 | 1/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.77 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.77 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22259431 | 0.89 | GABRA1 (0.73) | GABRA1GABRB2CYP3A4CYP1A2CYP11B1 | |
| SCHEMBL22259533 | 0.89 | GABRA1 (0.73) | GABRA1GABRB2CYP3A4CYP1A2CYP11B1 | |
| SCHEMBL22259496 | 0.89 | MAPK1 (0.75) | GABRA1GABRB2CYP3A4CYP1A2CYP11B1 | |
| SCHEMBL22259532 | 0.87 | MAPK1 (0.66) | GABRA1GABRB2CYP3A4CYP1A2CYP11B1 | |
| Etomidate SCHEMBL39487 | 0.87 | GABRA1 (1.00) | GABRA1GABRB2CYP3A4CYP1A2CYP11B1 | |
| S-Etomidate SCHEMBL39486 | 0.87 | GABRA1 (1.00) | GABRA1GABRB2CYP3A4CYP1A2CYP11B1 | |
| Amidate SCHEMBL1817757 | 0.87 | GABRA1 (1.00) | GABRA1GABRB2CYP3A4CYP1A2CYP11B1 | |
| Amidate SCHEMBL39485 | 0.87 | GABRA1 (1.00) | GABRA1GABRB2CYP3A4CYP1A2CYP11B1 | |
| Amidate SCHEMBL901536 | 0.86 | GABRA1 (0.97) | GABRA1GABRB2CYP3A4CYP1A2CYP11B1 | |
| Amidate SCHEMBL22502728 | 0.86 | GABRA1 (0.97) | GABRA1GABRB2CYP3A4CYP1A2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3587403-B1 | N-SUBSTITUTED IMIDAZOLE CARBOXYLATE COMPOUND, PREPARATION METHOD AND USE | WEST CHINA HOSPITAL SICHUAN UNIV (CN) | 2023-08-23 | — | — | EP | disclosed |
| US-11208385-B2 | N-substituted imidazole carboxylate compound, preparation method and use | WEST CHINA HOSPITAL, SICHUAN UNIVERSITY (CN) | 2021-12-28 | — | — | US | disclosed |
| US-20200231546-A1 | N-SUBSTITUTED IMIDAZOLE CARBOXYLATE COMPOUND, PREPARATION METHOD AND USE | WEST CHINA HOSPITAL, SICHUAN UNIVERSITY (CN) | 2020-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11208385-B2 | N-substituted imidazole carboxylate compound, preparation method and use | NR3C1, CYP2E1, CYP3A5 | GABRA1 25/4885GABRB2 114/4885CYP3A4 6/4885 |
| US-20200231546-A1 | N-SUBSTITUTED IMIDAZOLE CARBOXYLATE COMPOUND, PREPARATION METHOD AND USE | CHRM1, CYP2C18, CYP2E1 | GABRA1 11/4885GABRB2 53/4885CYP3A4 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.