Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | QPCT | Q16769 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20116129 | 0.78 | TUBB4A (0.50) | SMN1; SMN2LDHA | |
| SCHEMBL30552726 | 0.78 | TUBB4A (0.50) | SMN1; SMN2LDHA | |
| SCHEMBL22357989 | 0.78 | LDHA (0.54) | SMN1; SMN2LDHASCD5 | |
| SCHEMBL22357963 | 0.77 | SMN1; SMN2 (0.43) | SMN1; SMN2LDHASCD5RAB9AKMT2A | |
| SCHEMBL26999735 | 0.75 | TUBB4A (0.47) | SMN1; SMN2LDHARAB9A | |
| SCHEMBL30506269 | 0.75 | KMT2A (0.43) | SMN1; SMN2LDHASCD5RAB9AKMT2A | |
| SCHEMBL20116134 | 0.75 | KMT2A (0.43) | SMN1; SMN2LDHASCD5RAB9AKMT2A | |
| SCHEMBL22358346 | 0.74 | LDHA (0.40) | SMN1; SMN2LDHARAB9A | |
| SCHEMBL22357816 | 0.73 | LDHA (0.39) | SMN1; SMN2LDHASCD5RAB9AKMT2A | |
| SCHEMBL22357801 | 0.73 | SCD5 (0.40) | SMN1; SMN2LDHASCD5RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150423-A1 | METHODS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | YUMANITY THERAPEUTICS, INC. (US) | 2020-07-23 | — | — | WO | disclosed |