Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31498326 | 0.72 | SRD5A1 (0.38) | ALDH1A1SRD5A1CYP3A4 | |
| SCHEMBL414198 | 0.70 | NPC1 (0.52) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL597333 | 0.70 | DPP4 (0.49) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL22005789 | 0.68 | DPP4 (0.47) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL6455988 | 0.68 | ALDH1A1 (0.35) | ALDH1A1SRD5A1CYP3A4SMN1; SMN2 | |
| SCHEMBL6455983 | 0.68 | ALDH1A1 (0.35) | ALDH1A1SRD5A1CYP3A4SMN1; SMN2 | |
| SCHEMBL13254613 | 0.66 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL12670641 | 0.66 | DRD2 (0.47) | ALDH1A1SRD5A1CYP3A4MAPTNFKB1 | |
| SCHEMBL15759222 | 0.66 | SRD5A1 (0.40) | NPC1RAB9APOLBALDH1A1SRD5A1 | |
| SCHEMBL13961201 | 0.66 | SRD5A1 (0.40) | NPC1RAB9APOLBALDH1A1SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150423-A1 | METHODS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | YUMANITY THERAPEUTICS, INC. (US) | 2020-07-23 | — | — | WO | disclosed |