Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL22372373 | 0.99 | GAA (0.47) | GAACHRNB2CHRNA4FNTAFNTB | |
| SCHEMBL27368695 | 0.77 | KMT2A (0.56) | GAACHRNB2CHRNA4FNTAFNTB | |
| Hydrochloric Acid SCHEMBL29074406 | 0.71 | AOC3 (0.42) | MEN1KMT2A | |
| SCHEMBL17523046 | 0.71 | CHRNB2 (0.61) | CHRNB2CHRNA4LMNARECQLRIPK1 | |
| SCHEMBL27771997 | 0.70 | CHRNB2 (0.59) | CHRNB2CHRNA4LMNAGRM2RIPK1 | |
| SCHEMBL13829049 | 0.69 | FNTA (0.48) | GAACHRNB2CHRNA4FNTAFNTB | |
| SCHEMBL29055220 | 0.69 | RECQL (0.62) | GAARECQLKMT2A | |
| SCHEMBL12089140 | 0.69 | CHRNB2 (0.67) | CHRNB2CHRNA4LMNAGRM2RIPK1 | |
| SCHEMBL14454647 | 0.68 | LMNA (0.53) | GAACHRNB2CHRNA4FNTAFNTB | |
| SCHEMBL27258621 | 0.67 | CHRNB2 (0.59) | CHRNB2CHRNA4LMNAGRM2RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3222614-B1 | BIGUANIDE COMPOUND AND USE THEREOF | IMMUNOMET THERAPEUTICS INC (US) | 2020-07-29 | — | — | EP | disclosed |