Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | FNTA | P49354 | 1/20 | 0.54 |
| ▸ | FNTB | P49356 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27914432 | 0.80 | RECQL (0.53) | KMT2ALMNARECQLALDH1A1CHRNB2 | |
| SCHEMBL9843954 | 0.78 | SOAT1 (0.47) | KMT2AMEN1FNTAFNTBGAA | |
| SCHEMBL22260765 | 0.77 | GAA (0.48) | KMT2AMEN1FNTAFNTBGAA | |
| Hydrochloric Acid SCHEMBL22372373 | 0.76 | GAA (0.47) | KMT2AMEN1FNTAFNTBGAA | |
| SCHEMBL13829049 | 0.75 | FNTA (0.48) | KMT2AFNTAFNTBGAALMNA | |
| SCHEMBL14454647 | 0.75 | LMNA (0.53) | FNTAFNTBGAALMNAALDH1A1 | |
| SCHEMBL10752178 | 0.74 | LMNA (0.47) | KMT2AMEN1FNTAFNTBGAA | |
| SCHEMBL8470996 | 0.72 | RIPK1 (0.62) | KMT2ALMNARECQLALDH1A1CHRNB2 | |
| SCHEMBL27771997 | 0.71 | CHRNB2 (0.59) | LMNAALDH1A1CHRNB2CHRNA4CYP1A2 | |
| SCHEMBL25203986 | 0.71 | LMNA (0.55) | KMT2AMEN1FNTAFNTBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1051733-A | Acyl-CoA: cholesteryl transferase inhibitor | WARNER LAMBERT CO (US) | 1991-05-29 | — | — | CN | disclosed |