Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.53 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | CDK7 | P50613 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30608075 | 0.81 | PARP1 (0.56) | PARP1PDK2SCN9ALMNAGAA | |
| SCHEMBL5143960 | 0.81 | PARP1 (0.56) | PARP1PDK2SCN9ALMNAGAA | |
| SCHEMBL22263186 | 0.81 | PARP1 (0.48) | PARP1PDK2SCN9ALMNAGAA | |
| SCHEMBL4776527 | 0.79 | PARP1 (0.54) | PARP1PDK2SCN9ALMNAGAA | |
| SCHEMBL29733181 | 0.79 | PARP1 (0.58) | PARP1PDK2SCN9ALMNAGAA | |
| SCHEMBL6173688 | 0.78 | PARP1 (0.53) | PARP1PDK2SCN9ALMNAGAA | |
| SCHEMBL3511705 | 0.76 | PARP1 (0.47) | PARP1LMNAGAABCAT2KEAP1 | |
| SCHEMBL2484725 | 0.75 | PARP1 (0.49) | PARP1PDK2SCN9ALMNAGAA | |
| SCHEMBL26669294 | 0.74 | PARP1 (0.50) | PARP1PDK2SCN9ALMNAGAA | |
| SCHEMBL2975349 | 0.74 | PARP1 (0.39) | PARP1GAAIRAK4ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11166460-B2 | α-amino acrylate microbicide, and preparation method therefor and uses thereof | NANKAI UNIVERSITY (CN) | 2021-11-09 | — | — | US | disclosed |
| US-20200236935-A1 | a-Amino Acrylate microbicide, and preparation method therefor and uses thereof | UNIV NANKAI (CN) | 2020-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200236935-A1 | a-Amino Acrylate microbicide, and preparation method therefor and uses thereof | AASDHPPT, ACE, ADA | PARP1 1358/4885PDK2 3214/4885SCN9A 3224/4885 |
| US-11166460-B2 | α-amino acrylate microbicide, and preparation method therefor and uses thereof | ACE, AASDHPPT, DDT | PARP1 1364/4885PDK2 2801/4885SCN9A 2592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.