Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.38 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22263187 | 0.81 | PARP1 (0.53) | PARP1PDK2KEAP1NFE2L2SCN9A | |
| SCHEMBL6173681 | 0.80 | PARP1 (0.52) | PARP1PDK2KEAP1NFE2L2SCN9A | |
| SCHEMBL4776516 | 0.80 | PARP1 (0.52) | PARP1PDK2KEAP1NFE2L2SCN9A | |
| SCHEMBL30608075 | 0.76 | PARP1 (0.56) | PARP1PDK2KEAP1NFE2L2SCN9A | |
| SCHEMBL5143960 | 0.76 | PARP1 (0.56) | PARP1PDK2KEAP1NFE2L2SCN9A | |
| SCHEMBL29758514 | 0.75 | PARP1 (0.40) | PARP1PDK2LMNAGAASLC9A1 | |
| SCHEMBL27667504 | 0.75 | BCAT2 (0.49) | PARP1KEAP1NFE2L2LMNABCAT2 | |
| SCHEMBL14120523 | 0.75 | ALDH1A1 (0.43) | KEAP1NFE2L2LMNAGAASLC9A1 | |
| SCHEMBL29733181 | 0.74 | PARP1 (0.58) | PARP1PDK2KEAP1NFE2L2SCN9A | |
| SCHEMBL4776527 | 0.74 | PARP1 (0.54) | PARP1PDK2KEAP1NFE2L2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11166460-B2 | α-amino acrylate microbicide, and preparation method therefor and uses thereof | NANKAI UNIVERSITY (CN) | 2021-11-09 | — | — | US | disclosed |
| US-20200236935-A1 | a-Amino Acrylate microbicide, and preparation method therefor and uses thereof | UNIV NANKAI (CN) | 2020-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200236935-A1 | a-Amino Acrylate microbicide, and preparation method therefor and uses thereof | AASDHPPT, ACE, ADA | PARP1 1358/4885PDK2 3214/4885KEAP1 2258/4885 |
| US-11166460-B2 | α-amino acrylate microbicide, and preparation method therefor and uses thereof | ACE, AASDHPPT, DDT | PARP1 1364/4885PDK2 2801/4885KEAP1 2404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.