Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.44 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 5/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18519738 | 0.81 | PIK3CD (0.45) | IRAK4IRAK1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL22387457 | 0.78 | IRAK4 (0.45) | IRAK4IRAK1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL29013278 | 0.73 | ACVR1 (0.37) | IRAK4PIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL15576056 | 0.72 | CHRNB2 (0.39) | IRAK4IRAK1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL670597 | 0.72 | — | — | |
| SCHEMBL24151179 | 0.71 | ASIC3 (0.47) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL24290352 | 0.71 | JAK2 (0.47) | IRAK4IRAK1MKNK1PIM1PIM3 | |
| SCHEMBL24956331 | 0.70 | IRAK4 (0.56) | IRAK4IRAK1PIM1JAK2JAK1 | |
| SCHEMBL24958944 | 0.69 | CHRNB2 (0.40) | IRAK4IRAK1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL30576672 | 0.68 | PIK3CD (0.47) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3686196-A1 | POLYCYCLIC COMPOUND ACTING AS IDO INHIBITOR AND/OR IDO-HDAC DUAL INHIBITOR | Hangzhou Innogate Pharma Co., Ltd. (CN) | 2020-07-29 | — | — | EP | disclosed |