Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPIF | P30405 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19205812 | 0.89 | NPC1 (0.45) | PPIARORC | |
| SCHEMBL22270870 | 0.82 | TRPV1 (0.42) | TRPV1 | |
| SCHEMBL22271055 | 0.77 | TRPV1 (0.39) | TRPV1 | |
| SCHEMBL19205666 | 0.76 | WNT3A (0.43) | PPIARORC | |
| SCHEMBL18448279 | 0.76 | WNT3A (0.54) | RORC | |
| SCHEMBL19205607 | 0.75 | RORC (0.51) | RORC | |
| SCHEMBL19205813 | 0.75 | RORC (0.51) | RORC | |
| SCHEMBL19205608 | 0.75 | RORC (0.51) | RORC | |
| SCHEMBL28638482 | 0.74 | KCNJ5 (0.49) | TRPV1RORC | |
| SCHEMBL19205625 | 0.74 | KCNJ5 (0.46) | TRPV1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3686187-A1 | PROCESS FOR THE PREPARATION OF ROR GAMMA MODULATORS | Glenmark Pharmaceuticals S.A. (CH) | 2020-07-29 | — | — | EP | disclosed |