Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 14/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19205616 | 0.87 | SMN1; SMN2 (0.52) | TRPV1SMN1; SMN2GAARAB9ACYP2D6 | |
| SCHEMBL22271052 | 0.82 | PPIA (0.39) | TRPV1 | |
| SCHEMBL22271055 | 0.82 | TRPV1 (0.39) | TRPV1 | |
| SCHEMBL18448341 | 0.79 | RORC (0.52) | TRPV1CYP2D6PSEN1PSEN2APH1B | |
| SCHEMBL18448279 | 0.78 | WNT3A (0.54) | SMN1; SMN2RAB9ACYP2D6PSEN1PSEN2 | |
| SCHEMBL18449671 | 0.78 | RAB9A (0.49) | TRPV1SMN1; SMN2RAB9ACYP2D6PSEN1 | |
| SCHEMBL18447797 | 0.78 | PSEN1 (0.44) | TRPV1SMN1; SMN2GAARAB9ACYP2D6 | |
| SCHEMBL18448521 | 0.78 | RORC (0.49) | SMN1; SMN2GAARAB9ACYP2D6PSEN1 | |
| SCHEMBL18447801 | 0.77 | NPC1 (0.51) | TRPV1SMN1; SMN2RAB9AMAPTCYP2D6 | |
| SCHEMBL18447818 | 0.76 | SMN1; SMN2 (0.56) | SMN1; SMN2GAARAB9AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3686187-A1 | PROCESS FOR THE PREPARATION OF ROR GAMMA MODULATORS | Glenmark Pharmaceuticals S.A. (CH) | 2020-07-29 | — | — | EP | disclosed |