Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 15/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.53 |
| ▸ | AR | P10275 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | ESRRG | P62508 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TYR | P14679 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13609968 | 0.93 | ESR1 (0.73) | ESR1ESR2ARHSD17B10HPGD | |
| SCHEMBL686940 | 0.89 | ESR1 (0.62) | ESR1ESR2ARCYP3A4HSD17B10 | |
| SCHEMBL13609972 | 0.87 | ESR1 (0.76) | ESR1ESR2ARHSD17B10HPGD | |
| Bisphenol A SCHEMBL16581553 | 0.87 | ESR1 (0.83) | ESR1ESR2ARCYP3A4HSD17B10 | |
| SCHEMBL29473780 | 0.87 | ESR1 (0.83) | ESR1ESR2ARCYP3A4HSD17B10 | |
| SCHEMBL1862016 | 0.87 | ESR1 (0.83) | ESR1ESR2ARCYP3A4HSD17B10 | |
| SCHEMBL19204944 | 0.87 | ESR1 (0.83) | ESR1ESR2ARCYP3A4HSD17B10 | |
| SCHEMBL19884631 | 0.86 | ESR1 (0.63) | ESR1ESR2ARHSD17B10HPGD | |
| SCHEMBL9073140 | 0.86 | ESR1 (0.54) | ESR1ESR2ARCYP3A4HSD17B10 | |
| SCHEMBL352398 | 0.84 | ESR1 (0.72) | ESR1ESR2ARCYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2080750-B1 | RADIATION-SENSITIVE COMPOSITION | MITSUBISHI GAS CHEMICAL CO (JP) | 2020-07-29 | — | — | EP | disclosed |