SCHEMBL2227199

SCHEMBL2227199

CC(NCCCC#N)[Si](C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.37
GBA1 P04062 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2229774 0.94 TSHR (0.36) TSHRGBA1
SCHEMBL2227603 0.89 TSHR (0.34) TSHR
SCHEMBL8851480 0.77
SCHEMBL7855413 0.70 TSHR (0.42) TSHRGBA1
SCHEMBL28587256 0.69 SIGMAR1 (0.39)
SCHEMBL24230133 0.68 TSHR (0.40) TSHRGBA1
SCHEMBL12814068 0.67 LMNA (0.39) TSHR
SCHEMBL2229470 0.67 TSHR (0.39) TSHRGBA1
SCHEMBL25245178 0.67 TSHR (0.39) TSHRGBA1
SCHEMBL97294 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011091346-A2 POLYMERS FUNCTIONALIZED WITH NITRILE COMPOUNDS CONTAINING A PROTECTED AMINO GROUP BRIDGESTONE CORPORATION (JP) 2011-07-28 WO disclosed