Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | AHR | P35869 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAP2 | P11137 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954980 | 0.84 | KDM4E (0.57) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL5008079 | 0.84 | KDM4E (0.57) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL1253813 | 0.82 | EGFR (0.50) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL2800262 | 0.82 | KDM4E (0.57) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| Benzene SCHEMBL28244199 | 0.81 | MEN1 (0.58) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL29643083 | 0.79 | GABRA1 (0.49) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL9215592 | 0.79 | GABRA1 (0.49) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL3198815 | 0.79 | ALOX15 (0.68) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| Acetic Acid SCHEMBL28679441 | 0.78 | MAPT (0.60) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL10704376 | 0.77 | ALDH1A1 (0.61) | KDM4EMEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705279-A4 | TOPOLOGICALLY SEGREGATED, ENCODED SOLID PHASE LIBRARIES | SELECTIDE CORP (US) | 1999-03-24 | — | — | EP | claimed |
| EP-0705279-A1 | TOPOLOGICALLY SEGREGATED, ENCODED SOLID PHASE LIBRARIES | SELECTIDE CORPORATION (US) | 1996-04-10 | — | — | EP | claimed |
| WO-2011091152-A1 | INHIBITORS OF HEPATITIS C VIRUS INFECTION | GASTAMINZA PABLO (US) | 2011-07-28 | — | — | WO | disclosed |
| EP-2220026-A2 | INHIBITORS OF 17BETA-HYDROXYSTEROID DEHYDROGENASE | Sterix Limited (GB) | 2010-08-25 | — | — | EP | disclosed |
| WO-2010014744-A1 | INHIBITORS OF HEPATITIS C VIRUS INFECTION | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-02-04 | — | — | WO | disclosed |
| WO-2009066072-A2 | COMPOUND | STERIX LIMITED (GB) | 2009-05-28 | — | — | WO | disclosed |
| EP-1435962-A4 | TREATMENT OF TYPE I DIABETES | CELL PATHWAYS INC (US) | 2009-04-15 | — | — | EP | disclosed |
| EP-1730049-A1 | COSMETIC PORTION | Henkel Kommanditgesellschaft auf Aktien (DE) | 2006-12-13 | — | — | EP | disclosed |
| WO-2005085089-A1 | COSMETIC PORTION | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2005-09-15 | — | — | WO | disclosed |
| EP-1528924-A1 | MCH1R ANTAGONISTS | Astrazeneca AB (SE) | 2005-05-11 | — | — | EP | disclosed |
| EP-1435961-A4 | TREATMENT FOR LUPUS ERYTHEMATOSUS | CELL PATHWAYS INC (US) | 2005-04-20 | — | — | EP | disclosed |
| WO-2004004726-A1 | MCHIR ANTAGONISTS | ASTRAZENECA AB (SE) | 2004-01-15 | — | — | WO | disclosed |
| WO-2003017999-A1 | TREATMENT OF SCLERODERMA | CELL PATHWAYS, INC. (US) | 2003-03-06 | — | — | WO | disclosed |
| WO-2003017765-A1 | TREATMENT FOR CYSTIC FIBROSIS | CELL PATHWAYS, INC. (US) | 2003-03-06 | — | — | WO | disclosed |
| WO-2003017925-A2 | TREATMENT OF TYPE I DIABETES | CELL PATHWAYS, INC. (US) | 2003-03-06 | — | — | WO | disclosed |
| WO-2003017926-A2 | TREATMENT FOR LUPUS ERYTHEMATOSUS | CELL PATHWAYS, INC. (US) | 2003-03-06 | — | — | WO | disclosed |
| WO-2002067936-A1 | METHODS FOR TREATMENT OF INFLAMMATORY BOWEL DISEASE | CELL PATHWAYS, INC. (US) | 2002-09-06 | — | — | WO | disclosed |
| EP-1044187-A1 | N-BENZYL-3-INDENYLACETAMIDES DERIVATIVES FOR TREATING NEOPLASIA | OSI Pharmaceuticals, Inc. (US) | 2000-10-18 | — | — | EP | disclosed |
| WO-1999031065-A1 | N-BENZYL-3-INDENYLACETAMIDES DERIVATIVES FOR TREATING NEOPLASIA | CELL PATHWAYS, INC. (US) | 1999-06-24 | — | — | WO | disclosed |
| EP-0802902-A1 | INDOLE DERIVATIVES USEFUL IN THE TREATMENT OF OSTEOPOROSIS | Smithkline Beecham S.p.A. (IT) | 1997-10-29 | — | — | EP | disclosed |