Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ATP4A | P20648 | 2/20 | 0.38 |
| ▸ | ATP4B | P51164 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.37 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2228639 | 0.77 | RAB9A (0.49) | RAB9AALDH1A1ALOX5ARNPC1 | |
| SCHEMBL2228209 | 0.74 | ICMT (0.41) | RAB9AALDH1A1ALOX5ARNPC1 | |
| SCHEMBL2226898 | 0.67 | RAB9A (0.49) | RAB9AALDH1A1ALOX5ARNPC1 | |
| SCHEMBL2228583 | 0.66 | SLC6A2 (0.49) | RAB9AALDH1A1ARNPC1DPP4 | |
| SCHEMBL28805133 | 0.65 | CNR1 (0.44) | RAB9AALDH1A1ALOX5ARNPC1 | |
| SCHEMBL2227995 | 0.64 | RAB9A (0.39) | RAB9AALDH1A1ALOX5ARNPC1 | |
| SCHEMBL2224668 | 0.64 | LTA4H (0.47) | RAB9AALDH1A1ALOX5ARNPC1 | |
| SCHEMBL2224157 | 0.64 | RAB9A (0.49) | RAB9AALDH1A1NPC1KDM4ELMNA | |
| SCHEMBL2225312 | 0.64 | RAB9A (0.49) | RAB9AALDH1A1ALOX5NPC1KDM4E | |
| SCHEMBL2225676 | 0.64 | CNR2 (0.45) | RAB9AALDH1A1ALOX5ARNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011088181-A9 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. (US) | 2013-01-31 | — | — | WO | disclosed |
| EP-2533783-A1 | COMPOUNDS AND METHODS | Tempero Pharmaceuticals, Inc. (US) | 2012-12-19 | — | — | EP | disclosed |
| WO-2011088181-A1 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. (US) | 2011-07-21 | — | — | WO | disclosed |