Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 5/20 | 0.45 |
| ▸ | PGR | P06401 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29564114 | 1.00 | NR3C1 (0.45) | NR3C1PGRPOLBNR1I2MEN1 | |
| SCHEMBL22273620 | 0.84 | NR3C1 (0.46) | NR3C1PGRPOLBNR1I2MEN1 | |
| SCHEMBL28296376 | 0.82 | NR3C1 (0.47) | NR3C1PGRPOLBNR1I2MEN1 | |
| SCHEMBL22273580 | 0.80 | NR3C1 (0.42) | NR3C1PGRPOLBNR1I2MEN1 | |
| SCHEMBL22273724 | 0.79 | RORC (0.46) | NR3C1PGRPOLBNR1I2MEN1 | |
| SCHEMBL22273619 | 0.79 | NR3C1 (0.42) | NR3C1PGRPOLBNR1I2MEN1 | |
| SCHEMBL22273579 | 0.77 | NR3C1 (0.53) | NR3C1PGRPOLBNR1I2MEN1 | |
| SCHEMBL22273557 | 0.77 | MEN1 (0.54) | NR3C1PGRPOLBNR1I2MEN1 | |
| SCHEMBL29564093 | 0.76 | RORC (0.49) | NR3C1PGRPOLBNR1I2MEN1 | |
| SCHEMBL29563877 | 0.76 | RORC (0.42) | NR3C1PGRPOLBNR1I2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651297-B | N-benzyl-N-aryl sulfonamide derivative and preparation and application thereof | 杭州壹瑞医药科技有限公司 | 2022-05-27 | — | — | CN | disclosed |
| EP-3915978-A1 | N-BENZYL-N-ARYLSULFONAMIDE DERIVATIVE AND PREPARATION AND USE THEREOF | Hangzhou Yirui Pharmaceutical Technology Co., Ltd (CN) | 2021-12-01 | — | — | EP | disclosed |
| WO-2020151687-A1 | N-BENZYL-N-ARYLSULFONAMIDE DERIVATIVE AND PREPARATION AND USE THEREOF | 杭州壹瑞医药科技有限公司 | 2020-07-30 | — | — | WO | disclosed |