SCHEMBL22274530

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17828459	0.90	MEN1 (0.42)	KDM4EKMT2AL3MBTL1ALDH1A1MEN1
	SCHEMBL22274423	0.87	KDM4E (0.42)	KDM4EHSP90AA1HSP90AB1KMT2AL3MBTL1
	SCHEMBL17897560	0.84	DUSP3 (0.38)	KDM4EKMT2AL3MBTL1ALDH1A1MEN1
	SCHEMBL17897550	0.83	MEN1 (0.38)	KDM4EKMT2AL3MBTL1ALDH1A1MEN1
	SCHEMBL17897542	0.83	MEN1 (0.37)	KDM4EKMT2AL3MBTL1ALDH1A1MEN1
	SCHEMBL17828458	0.82	MEN1 (0.45)	KDM4EKMT2AL3MBTL1ALDH1A1MEN1
	SCHEMBL17897534	0.82	L3MBTL1 (0.39)	KDM4EKMT2AL3MBTL1ALDH1A1MEN1
	SCHEMBL22064954	0.82	L3MBTL1 (0.39)	KDM4EKMT2AL3MBTL1ALDH1A1MEN1
	SCHEMBL17897530	0.82	L3MBTL1 (0.39)	KDM4EKMT2AL3MBTL1ALDH1A1MEN1
	SCHEMBL17897543	0.82	L3MBTL1 (0.46)	KDM4EKMT2AL3MBTL1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.