Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 10/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | FASN | P49327 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2227491 | 0.92 | HDAC4 (0.46) | HDAC4HDAC6HDAC8HDAC2 | |
| SCHEMBL2227597 | 0.85 | HDAC4 (0.48) | HDAC4HDAC6HDAC8HDAC2 | |
| SCHEMBL2226069 | 0.85 | KDM4E (0.55) | HDAC4HDAC6HDAC8HDAC2 | |
| SCHEMBL2227516 | 0.82 | FASN (0.49) | HDAC4HDAC6HDAC8HDAC2FASN | |
| SCHEMBL2224982 | 0.81 | HDAC4 (0.57) | HDAC4HDAC6HDAC8HDAC2MGLL | |
| SCHEMBL2227494 | 0.78 | HDAC4 (0.46) | HDAC4HDAC6HDAC8HDAC2 | |
| SCHEMBL2226604 | 0.78 | SLC6A7 (0.62) | HDAC4HDAC6HDAC8HDAC2MGLL | |
| SCHEMBL2223596 | 0.77 | HDAC4 (0.52) | HDAC4HDAC6HDAC8HDAC2HDAC1 | |
| SCHEMBL2228753 | 0.77 | HDAC4 (0.56) | HDAC4HDAC6HDAC8HDAC2HDAC1 | |
| SCHEMBL2228781 | 0.76 | HSD11B1 (0.63) | HDAC4HDAC6HDAC8HDAC2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011088192-A1 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. (US) | 2011-07-21 | — | — | WO | disclosed |