SCHEMBL22277134

SCHEMBL22277134

c1ccc2cc3c(cc2c1)c1cc2c(cc1n3-c1nc3ccccc3nc1-c1cccc3ccccc13)sc1ccccc12

nearest known ligand 0.32

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
MAPT P10636 2/20 0.32
POLB P06746 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
PGK1 P00558 1/20 0.32
GPR3 P46089 1/20 0.30
GSR P00390 1/20 0.30
HPGD P15428 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
GSK3B P49841 1/20 0.30
CDK5 Q00535 1/20 0.30
CDK5R1 Q15078 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21942024 0.94 TUBB4A (0.33) ALDH1A1MAPTPOLBTDP1L3MBTL1
SCHEMBL21941896 0.89 TUBB4A (0.33) ALDH1A1MAPTPOLBTDP1L3MBTL1
SCHEMBL22277138 0.87 ESR1 (0.37) ALDH1A1MAPTPOLBTDP1L3MBTL1
SCHEMBL22277121 0.86 ALDH1A1 (0.33) ALDH1A1MAPTPOLBTDP1L3MBTL1
SCHEMBL21213368 0.84 TUBB4A (0.38) ALDH1A1MAPTPGK1GSRHPGD
SCHEMBL21213126 0.83 CYP1A2 (0.34) GSRHPGDRAB9ASMN1; SMN2KDM4E
SCHEMBL21213455 0.83 ALOX5 (0.37) MAPTGSRHPGDRAB9ASMN1; SMN2
SCHEMBL21941970 0.83 CYP1A2 (0.32) GSR
SCHEMBL21942099 0.82 GSR (0.32) PGK1GSR
SCHEMBL21168812 0.79 KDM4E (0.40) ALDH1A1MAPTL3MBTL1GSRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020153652-A1 COMPOUND, AND ORGANIC LIGHT EMITTING ELEMENT INCLUDING SAME 주식회사 엘지화학 2020-07-30 WO disclosed