Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19985394 | 0.99 | ESR2 (0.34) | ESR2DGAT1SOAT1KDM1ACYP2C9 | |
| SCHEMBL22277364 | 0.94 | ESR2 (0.31) | ESR2DGAT1SOAT1KDM1ACYP2C9 | |
| SCHEMBL22277452 | 0.94 | FFAR4 (0.37) | ESR2DGAT1SOAT1KDM1ACYP2C9 | |
| SCHEMBL22277362 | 0.92 | GPR119 (0.33) | ESR2 | |
| SCHEMBL8933815 | 0.92 | KDM1A (0.37) | KDM1ACYP2C9FPR2GRIN1GRIN2B | |
| SCHEMBL19985396 | 0.92 | GABRA1 (0.38) | ESR2DGAT1SOAT1CYP2C9FPR2 | |
| SCHEMBL17522404 | 0.91 | GRIN1 (0.30) | GRIN1GRIN2B | |
| SCHEMBL26455653 | 0.91 | ESR2 (0.39) | ESR2DGAT1SOAT1KDM1ACYP2C9 | |
| SCHEMBL19985400 | 0.91 | CNR2 (0.35) | ESR2DGAT1SOAT1CYP2C9ALDH1A1 | |
| SCHEMBL22277562 | 0.90 | FFAR4 (0.38) | ESR2DGAT1ALDH1A1MAPTFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200239775-A1 | TETRACYCLIC LIQUID CRYSTAL COMPOUND HAVING DIATOMIC BONDING GROUP AND 2,3-DIFLUOROPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2020-07-30 | — | — | US | disclosed |