Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 2/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22277359 | 1.00 | GPR119 (0.32) | GPR119FPR2KDM1AFGFR1FGFR2 | |
| SCHEMBL22277495 | 0.92 | GABRA1 (0.33) | GPR119 | |
| SCHEMBL26209579 | 0.92 | GPR119 (0.36) | GPR119FPR2KDM1AFGFR1FGFR2 | |
| SCHEMBL15681400 | 0.91 | KDM1A (0.35) | FPR2KDM1AFGFR1FGFR2 | |
| SCHEMBL22277362 | 0.90 | GPR119 (0.33) | GPR119 | |
| SCHEMBL22269483 | 0.90 | KDM1A (0.34) | FPR2KDM1AFGFR1FGFR2 | |
| SCHEMBL24113790 | 0.88 | ESR2 (0.31) | FPR2 | |
| SCHEMBL24462247 | 0.87 | GPR119 (0.35) | GPR119FPR2KDM1AFGFR1FGFR2 | |
| SCHEMBL22277436 | 0.87 | KDM1A (0.33) | FPR2KDM1AFGFR1FGFR2 | |
| SCHEMBL12760221 | 0.87 | FPR2 (0.31) | FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200239775-A1 | TETRACYCLIC LIQUID CRYSTAL COMPOUND HAVING DIATOMIC BONDING GROUP AND 2,3-DIFLUOROPHENYLENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2020-07-30 | — | — | US | disclosed |