Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 9/20 | 0.92 |
| ▸ | ALOX12 | P18054 | 7/20 | 0.92 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.92 |
| ▸ | RECQL | P46063 | 3/20 | 0.92 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.92 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.92 |
| ▸ | MEN1 | O00255 | 2/20 | 0.92 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.92 |
| ▸ | ESR1 | P03372 | 2/20 | 0.92 |
| ▸ | TP53 | P04637 | 2/20 | 0.92 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.92 |
| ▸ | HPGD | P15428 | 2/20 | 0.92 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.92 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.92 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.92 |
| ▸ | FOS | P01100 | 2/20 | 0.92 |
| ▸ | TTR | P02766 | 2/20 | 0.92 |
| ▸ | JUN | P05412 | 2/20 | 0.92 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.92 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.92 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Masoprocol SCHEMBL3818 | 0.96 | ALOX15 (1.00) | ALOX15ALOX12KDM4ERECQLHIF1A | |
| Nordihydroguaiaretic Acid SCHEMBL29434238 | 0.96 | ALOX15 (1.00) | ALOX15ALOX12KDM4ERECQLHIF1A | |
| Nordihydroguaiaretic Acid SCHEMBL29434237 | 0.96 | ALOX15 (1.00) | ALOX15ALOX12KDM4ERECQLHIF1A | |
| Nordihydroguaiaretic Acid SCHEMBL135976 | 0.96 | ALOX15 (1.00) | ALOX15ALOX12KDM4ERECQLHIF1A | |
| Masoprocol SCHEMBL29350884 | 0.96 | ALOX15 (1.00) | ALOX15ALOX12KDM4ERECQLHIF1A | |
| Nordihydroguaiaretic Acid SCHEMBL13906133 | 0.96 | ALOX15 (1.00) | ALOX15ALOX12KDM4ERECQLHIF1A | |
| Masoprocol SCHEMBL29355090 | 0.96 | ALOX15 (1.00) | ALOX15ALOX12KDM4ERECQLHIF1A | |
| Masoprocol SCHEMBL28156467 | 0.94 | ALOX15 (0.96) | ALOX15ALOX12KDM4ERECQLHIF1A | |
| SCHEMBL28992632 | 0.91 | ALOX15 (0.76) | ALOX15ALOX12KDM4ERECQLHIF1A | |
| Masoprocol SCHEMBL2304515 | 0.90 | ALOX15 (0.88) | ALOX15ALOX12KDM4ERECQLHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103768754-A | Fire-extinguishment composition containing unsaturated hydrocarbon compounds and derivatives thereof | XI AN JIAN RUI SAFETY EMERGENCY EQUIPMENT LTD LIABILITY COMPANY | 2014-05-07 | — | — | CN | claimed |
| CN-117428187-A | Method for preparing carbon-coated copper by in-situ reduction of polydopamine-like copper oxide, carbon-coated copper and application | 深圳大学 | 2024-01-23 | — | — | CN | disclosed |
| CN-103768754-B | Fire extinguishing composition containing unsaturated hydrocarbon compound and derivatives thereof | 湖北及安盾消防科技有限公司 | 2020-10-13 | — | — | CN | disclosed |
| US-20170233386-A1 | Compounds Which Have a Protective Activity with Respect to the Action of Toxins and of Viruses with an Intracellular Mode of Action | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2017-08-17 | — | — | US | disclosed |
| US-20160083355-A1 | COMPOUNDS WHICH HAVE A PROTECTIVE ACTIVITY WITH RESPECT TO THE ACTION OF TOXINS AND OF VIRUSES WITH AN INTRACELLULAR MODE OF ACTION | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2016-03-24 | — | — | US | disclosed |
| CN-103768754-A | Fire-extinguishment composition containing unsaturated hydrocarbon compounds and derivatives thereof | XI AN JIAN RUI SAFETY EMERGENCY EQUIPMENT LTD LIABILITY COMPANY | 2014-05-07 | — | — | CN | disclosed |
| US-20120283249-A1 | Novel compounds which have a protective activity with respect to the action of toxins and of viruses with an intracellular mode of action | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2012-11-08 | — | — | US | disclosed |
| US-20110166192-A1 | PROCESS FOR CHARGING A POLYMERIC PRODUCT WITH ATTRIBUTE IMPARTING AGENT(S) | ADITYA BIRLA SCIENCE & TECHNOLOGY CO. LTD. (IN) | 2011-07-07 | — | — | US | disclosed |
| EP-1549301-A2 | A METHOD FOR USING TETHERED BIS(POLYHYDROXYPHENYLS) AND O-ALKYL DERIVATIVES THEREOF IN TREATING INFLAMMATORY CONDITIONS OF THE CENTRAL NERVOUS SYSTEM | Oklahoma Medical Research Foundation (US) | 2005-07-06 | — | — | EP | disclosed |
| WO-2003103583-A2 | A METHOD FOR USING TETHERED BIS(POLYHYDROXYPHENYLS) AND O-ALKYL DERIVATIVES THEREOF IN TREATING INFLAMMATORY CONDITIONS OF THE CENTRAL NERVOUS SYSTEM | OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) | 2003-12-18 | — | — | WO | disclosed |
| EP-0265514-B1 | MEDICAMENTS FOR INHIBITING SKIN WRINKLING | BLOCK DRUG COMPANY (US) | 1993-03-31 | — | — | EP | disclosed |
| EP-0288534-B1 | COMPOSITIONS OF CATECHOLIC BUTANES WITH ZINC | CHEMEX PHARMACEUTICALS, INC. (US) | 1991-12-18 | — | — | EP | disclosed |
| US-5008294-A | Topical administration | CHEMEX PHARMACEUTICALS, INC. (US) | 1991-04-16 | — | — | US | disclosed |
| EP-0265514-A4 | Medicaments for inhibiting skin wrinkling. | CALIFORNIA HEALTH TECHNOLOGIES (US) | 1990-01-11 | — | — | EP | disclosed |
| US-4880637-A | ALCOHOLS, ETHERS OR ESTERS, AS ANTITUMOR AGENTS, SKIN DISORDERS | CHEMEX PHARMACEUTICALS, INC. (US) | 1989-11-14 | — | — | US | disclosed |
| WO-1988003806-A1 | PHARMACOLOGICALLY ACTIVE COMPOSITIONS OF CATECHOLIC BUTANES WITH ZINC | CHEMEX PHARMACEUTICALS, INC. (US) | 1988-06-02 | — | — | WO | disclosed |
| EP-0265514-A1 | Medicaments for inhibiting skin wrinkling. | CALIFORNIA HEALTH TECHNOLOGIES (US) | 1988-05-04 | — | — | EP | disclosed |
| WO-1988001509-A1 | PHARMACOLOGICALLY ACTIVE COMPOSITIONS OF CATECHOLIC BUTANES WITH ZINC | CHEMEX PHARMACEUTICALS, INC. (US) | 1988-03-10 | — | — | WO | disclosed |
| WO-1987006829-A1 | METHOD FOR INHIBITING AGING | CALIFORNIA HEALTH TECHNOLOGIES (US) | 1987-11-19 | — | — | WO | disclosed |
| US-3934034-A | Hydroxy substituted diphenylalkyls for treatment of lipidemia | SANDOZ, INC. (US) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283249-A1 | Novel compounds which have a protective activity with respect to the action of toxins and of viruses with an intracellular mode of action | HAVCR2, MAVS, ANTXR2 | ALOX15 4418/4885ALOX12 4559/4885KDM4E 1528/4885 |
| US-20160083355-A1 | COMPOUNDS WHICH HAVE A PROTECTIVE ACTIVITY WITH RESPECT TO THE ACTION OF TOXINS AND OF VIRUSES WITH AN INTRACELLULAR MODE OF ACTION | HAVCR2, MAVS, ANTXR2 | ALOX15 4522/4885ALOX12 4636/4885KDM4E 1212/4885 |
| US-20170233386-A1 | Compounds Which Have a Protective Activity with Respect to the Action of Toxins and of Viruses with an Intracellular Mode of Action | HAVCR2, MAVS, ANTXR2 | ALOX15 4522/4885ALOX12 4636/4885KDM4E 1212/4885 |
| US-20110166192-A1 | PROCESS FOR CHARGING A POLYMERIC PRODUCT WITH ATTRIBUTE IMPARTING AGENT(S) | IMPA1, PARG, AGPS | ALOX15 2170/4885ALOX12 2144/4885KDM4E 2911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.