Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13334305 | 0.87 | MAPT (0.55) | MAPTIDO1L3MBTL1MEN1KMT2A | |
| SCHEMBL21780574 | 0.87 | SYK (0.52) | MAPTIDO1L3MBTL1MEN1KMT2A | |
| SCHEMBL13622021 | 0.84 | IDO1 (0.56) | MAPTIDO1L3MBTL1MEN1KMT2A | |
| SCHEMBL15738439 | 0.81 | LMNA (0.71) | MAPTIDO1L3MBTL1MEN1KMT2A | |
| SCHEMBL20825713 | 0.81 | LMNA (0.71) | MAPTIDO1L3MBTL1MEN1KMT2A | |
| SCHEMBL21106167 | 0.80 | L3MBTL1 (0.56) | MAPTIDO1L3MBTL1SYKLMNA | |
| SCHEMBL25957572 | 0.80 | L3MBTL1 (0.56) | MAPTIDO1L3MBTL1SYKLMNA | |
| SCHEMBL30316999 | 0.80 | SMN1; SMN2 (0.59) | MAPTIDO1L3MBTL1SYKLMNA | |
| SCHEMBL20196937 | 0.80 | L3MBTL1 (0.58) | MAPTIDO1L3MBTL1SYKLMNA | |
| SCHEMBL19608402 | 0.80 | SYK (0.60) | MAPTIDO1MEN1KMT2ASYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020151682-A1 | MACROCYCLIC IMMUNOMODULATOR | 成都先导药物开发股份有限公司 | 2020-07-30 | — | — | WO | disclosed |