Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.53 |
| ▸ | PPARD | Q03181 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22263501 | 0.82 | PPARD (0.47) | PPARAPPARDALDH1A1GAAKDM4E | |
| SCHEMBL28293113 | 0.78 | TSHR (0.59) | PPARAPPARDTSHRALDH1A1GAA | |
| SCHEMBL17584292 | 0.74 | ALDH1A1 (0.48) | PPARAPPARDTSHRALDH1A1GAA | |
| SCHEMBL27498521 | 0.73 | TSHR (0.54) | PPARAPPARDTSHRALDH1A1GAA | |
| SCHEMBL22507637 | 0.73 | PPARA (0.85) | PPARAPPARDALDH1A1GAAKDM4E | |
| SCHEMBL4228872 | 0.72 | KDM4E (0.61) | TSHRALDH1A1GAAKDM4EMEN1 | |
| SCHEMBL3340831 | 0.72 | LMNA (0.77) | TSHRALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL2913722 | 0.71 | ALDH1A1 (0.57) | PPARAALDH1A1GAAKDM4EMEN1 | |
| SCHEMBL15563826 | 0.71 | ALDH1A1 (0.52) | PPARAPPARDALDH1A1GAAKDM4E | |
| SCHEMBL17584653 | 0.71 | ALDH1A1 (0.43) | PPARAPPARDTSHRALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11332457-B2 | Aromatic compound, pharmaceutical composition and use thereof | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2022-05-17 | — | — | US | disclosed |
| US-20200277277-A1 | AROMATIC COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2020-09-03 | — | — | US | disclosed |
| US-20200239429-A1 | AROMATIC COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2020-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11332457-B2 | Aromatic compound, pharmaceutical composition and use thereof | PPARD, PPARA, PPARG | PPARA 2/4885PPARD 1/4885TSHR 1420/4885 |
| US-20200277277-A1 | AROMATIC COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | PPARD, PPARA, PPARG | PPARA 2/4885PPARD 1/4885TSHR 1420/4885 |
| US-20200239429-A1 | AROMATIC COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | PPARD, PPARA, PPARG | PPARA 2/4885PPARD 1/4885TSHR 1420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.