Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.51 |
| ▸ | KDM1A | O60341 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | STAT3 | P40763 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7544859 | 0.79 | SMN1; SMN2 (0.50) | TLR8HTTSMN1; SMN2STAT3ALDH1A1 | |
| SCHEMBL27498521 | 0.79 | TSHR (0.54) | TSHRTLR8KDM1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL27929761 | 0.79 | TLR8 (0.47) | TSHRTLR8KDM1AHTTSMN1; SMN2 | |
| SCHEMBL28310888 | 0.78 | TLR8 (0.68) | TSHRTLR8HTTSMN1; SMN2STAT3 | |
| SCHEMBL22278945 | 0.78 | PPARA (0.53) | TSHRHTTSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL28102697 | 0.75 | PDGFRB (0.67) | TSHRTLR8KDM1AHTTALDH1A1 | |
| SCHEMBL27696506 | 0.75 | MAPT (0.59) | TSHRTLR8KDM1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL22631546 | 0.72 | NQO2 (0.55) | TSHRKDM1ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8560716 | 0.72 | TSHR (0.49) | TSHRKDM1ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL3461189 | 0.72 | KDM4E (0.64) | TSHRTLR8KDM1AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641056-A | Pharmaceutical composition | 协和发酵麒麟株式会社 | 2019-04-16 | — | — | CN | disclosed |