Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 3/20 | 0.48 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.46 |
| ▸ | TCF7L2 | Q9NQB0 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3053519 | 0.90 | CACNA1B (0.47) | CACNA1BCACNA1HKDM4EALDH1A1CTNNB1 | |
| Hydrochloric Acid SCHEMBL4738978 | 0.89 | CACNA1B (0.46) | CACNA1BCACNA1HKDM4EALDH1A1CTNNB1 | |
| SCHEMBL22279054 | 0.86 | KDM4E (0.57) | KDM4EALDH1A1CTNNB1TCF7L2ACHE | |
| SCHEMBL22279043 | 0.83 | P4HTM (0.50) | CACNA1BCACNA1HKDM4EALDH1A1LMNA | |
| SCHEMBL22279049 | 0.81 | P4HTM (0.51) | CACNA1BCACNA1HKDM4EALDH1A1SIGMAR1 | |
| SCHEMBL14504164 | 0.81 | HTT (0.54) | ALDH1A1CTNNB1TCF7L2LMNAALOX15 | |
| SCHEMBL2464412 | 0.77 | GAA (0.67) | CACNA1BCACNA1HKDM4EALDH1A1LMNA | |
| SCHEMBL22279092 | 0.77 | CNR2 (0.45) | CACNA1BCACNA1HKDM4EALDH1A1P4HTM | |
| SCHEMBL30635494 | 0.75 | CACNA1B (0.50) | CACNA1BCACNA1HKDM4EALDH1A1CTNNB1 | |
| SCHEMBL22278918 | 0.75 | ACHE (0.58) | KDM4EACHEGAAMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020151686-A1 | N-HETEROARYL SULFONAMIDE DERIVATIVE, PREPARATION AND USE THEREOF IN TREATMENT OF AUTOIMMUNE DISEASES | 杭州壹瑞医药科技有限公司 | 2020-07-30 | — | — | WO | disclosed |