Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.49 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.45 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.45 |
| ▸ | ELOVL1 | Q9BW60 | 3/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22279049 | 0.99 | P4HTM (0.51) | P4HTMCACNA1BCACNA1HLMNAKDM4E | |
| SCHEMBL22279080 | 0.87 | ALDH1A1 (0.53) | CACNA1BKDM4EALDH1A1KITSMN1; SMN2 | |
| SCHEMBL22279048 | 0.86 | GAA (0.55) | P4HTMLMNAKDM4EALDH1A1KCNQ3 | |
| SCHEMBL22279042 | 0.85 | P4HTM (0.47) | P4HTMCACNA1BCACNA1HLMNAKDM4E | |
| SCHEMBL22279044 | 0.83 | CACNA1B (0.48) | P4HTMCACNA1BCACNA1HLMNAKDM4E | |
| SCHEMBL22279046 | 0.81 | GAA (0.46) | P4HTMCACNA1BLMNAKDM4EOPRM1 | |
| SCHEMBL22279027 | 0.81 | RXFP1 (0.48) | P4HTMCACNA1BCACNA1HLMNAKDM4E | |
| SCHEMBL3058922 | 0.80 | HRH4 (0.53) | KDM4EGAAL3MBTL1MAPTALOX15 | |
| SCHEMBL4738295 | 0.80 | BPTF (0.51) | P4HTMLMNAKDM4EGAAL3MBTL1 | |
| SCHEMBL4737532 | 0.80 | GAA (0.51) | LMNAKDM4EALDH1A1KCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020151686-A1 | N-HETEROARYL SULFONAMIDE DERIVATIVE, PREPARATION AND USE THEREOF IN TREATMENT OF AUTOIMMUNE DISEASES | 杭州壹瑞医药科技有限公司 | 2020-07-30 | — | — | WO | disclosed |