Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 2/20 | 0.50 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP4 | P49662 | 1/20 | 0.43 |
| ▸ | CASP5 | P51878 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | IDH2 | P48735 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3053519 | 0.85 | CACNA1B (0.47) | CACNA1BCACNA1HKDM4EALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL4738978 | 0.84 | CACNA1B (0.46) | CACNA1BCACNA1HKDM4EALDH1A1MAPT | |
| SCHEMBL30635491 | 0.84 | MAPT (0.51) | CACNA1BCACNA1HKDM4EALDH1A1MAPT | |
| SCHEMBL14503578 | 0.76 | CASP1 (0.53) | CASP1CASP4CASP5KDM4EALDH1A1 | |
| SCHEMBL22279044 | 0.75 | CACNA1B (0.48) | CACNA1BCACNA1HKDM4EALDH1A1ACHE | |
| SCHEMBL23341097 | 0.75 | OGA (0.45) | CASP1CASP4CASP5KDM4EMAPT | |
| SCHEMBL24968333 | 0.73 | OGA (0.46) | CASP1CASP4CASP5KDM4EMAPT | |
| SCHEMBL7345712 | 0.71 | FFAR1 (0.68) | CACNA1BCACNA1HALDH1A1FFAR1MAPT | |
| SCHEMBL14503784 | 0.69 | MAPT (0.56) | TRPV1CASP1CASP4CASP5ALDH1A1 | |
| SCHEMBL12198381 | 0.68 | KDM4E (0.51) | CASP1CASP4CASP5KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023229380-A1 | HETEROCYCLIC COMPOUND AS DIACYLGLYCEROL KINASE INHIBITOR AND USE THEREOF | 주식회사 엘지화학 | 2023-11-30 | — | — | WO | disclosed |