Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12307502 | 0.82 | TP53 (0.41) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL22280605 | 0.77 | NPC1 (0.45) | NPC1RAB9AMAPTTP53 | |
| SCHEMBL12307485 | 0.72 | KMT2A (0.46) | NPC1MAPTMEN1KMT2ALMNA | |
| SCHEMBL12307413 | 0.71 | RIPK1 (0.38) | NPC1MAPTMEN1KMT2AHTT | |
| SCHEMBL12307503 | 0.71 | HTR1A (0.42) | MAPTLMNAHTT | |
| SCHEMBL12307508 | 0.69 | ALDH1A1 (0.38) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL12307494 | 0.68 | GRM5 (0.58) | — | |
| SCHEMBL12307488 | 0.68 | PIK3CG (0.45) | — | |
| SCHEMBL12307409 | 0.68 | GRM5 (0.60) | — | |
| SCHEMBL22279537 | 0.67 | NPC1 (0.34) | NPC1RAB9AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020153434-A1 | PYRAZOLE COMPOUND | 第一三共株式会社 | 2020-07-30 | — | — | WO | disclosed |